Detection and characterization of hepatic tumors: value of combined helical CT hepatic arteriography and CT during arterial portography.

Detection and characterization of hepatic tumors: value of combined helical CT hepatic arteriography and CT during arterial portography. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Detection and characterization of hepatic tumors: value of combined helical CT hepatic arteriography and CT during arterial portography. Abstract Text:

M Kanematsu,H Hoshi,T Imaeda,T Murakami,Y Inaba,R Yokoyama,H Nakamura,

OBJECTIVE: The purpose of our study was to evaluate the diagnostic accuracy of combining helical CT hepatic arteriography (CTA) with helical CT during arterial portography (CTAP) for detecting and characterizing hepatic tumors. MATERIALS AND METHODS: From January 1994 to September 1995, combined helical CTA and CTAP were performed in 52 patients (38 men and 14 women, 37-83 years old [mean, 64.1 years old]) with suspected primary or metastatic hepatic tumors before they were evaluated for hepatic resection. Retrospectively, two radiologists reviewed the CTAP images alone and subsequently matched CTA and CTAP images. The radiologists recorded a confidence level on a five-point scale for their evaluation of visible perfusion abnormalities as true lesions, and diagnostic accuracy was assessed using receiver-operating-characteristic analysis. Using the data sets obtained at the interpretation sessions by the radiologists, we determined sensitivities for CTAP alone and for combined CTA and CTAP in 28 malignant hepatic tumors that were confirmed in 19 patients who underwent definitive surgery. RESULTS: CTA revealed one hepatocellular carcinoma in a patient with severe cirrhosis and six adenomatous hyperplasias in another cirrhotic patient that CTAP failed to reveal. In comparison with CTAP alone, the combination of CTA and CTAP allowed significantly more accurate detection of lesions (area under receiver-operating-characteristic curve: 0.889 for CTAP alone versus 0.954 for CTA and CTAP combined, p < .01). The combination of CTA and CTAP also significantly raised the accuracy for characterizing hepatic tumors. Sensitivities for malignant hepatic tumors revealed in the 19 patients who underwent surgery were identical: 93% (26 of 28 tumors) with CTAP alone and with CTA and CTAP combined. CONCLUSION: Although combining CTA and CTAP does not significantly increase sensitivity for detecting hepatic tumors, the combined techniques significantly raise specificity in detecting hepatic tumors and accuracy in characterizing hepatic tumors.

Detection and characterization of hepatic tumors: value of combined helical CT hepatic arteriography and CT during arterial portography. Publishing Authors By Initials

M Kanematsu,H Hoshi,T Imaeda,T Murakami,Y Inaba,R Yokoyama,H Nakamura,

For similar tomography, x-ray computed research abstracts see: tomography, x-ray computed research

PUBMED ID PMID:

MEDLINE DATE:

Detection and characterization of hepatic tumors: value of combined helical CT hepatic arteriography and CT during arterial portography. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: AJR. American journal of roentgenology

VOLUME: 168

Page Numbers: 1193-8

Journal Abbreviation:

ISSN: 0361-803X

DAY: 15

MONTH: May

YEAR: 1997

Detection and characterization of hepatic tumors: value of combined helical CT hepatic arteriography and CT during arterial portography. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 7708173

Detection and characterization of hepatic tumors: value of combined helical CT hepatic arteriography and CT during arterial portography. Keywords Mesh Terms:

KEYWORDS: Tomography, X-Ray Computed

MESH TERMS: methods

Chemical & Substance for Abstract: Detection and characterization of hepatic tumors: value of combined helical CT hepatic arteriography and CT during arterial portography. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Detection and characterization of hepatic tumors: value of combined helical CT hepatic arteriography and CT during arterial portography.

AFFILIATION: Department of Radiology, Gifu University School of Medicine, Japan.

Country: UNITED STATES

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: AJR Am J Roentgenol

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Detection and characterization of hepatic tumors: value of combined helical CT hepatic arteriography and CT during arterial portography Related Publications

• A 3 T superconducting magnet for long-run magnetic Compton-scattering experiments.
• A compact superconducting ring as a radiation source for X-ray crystallography.
• Administration of hepatitis B vaccine in winter as a significant predictor of the poor effectiveness of vaccination in rural Mongolia: evidence from a nationwide survey.
• Altered whisker patterns induced by ectopic expression of Shh are topographically represented by barrels.
• Association of ulcerative colitis with rare VNTR alleles of the human intestinal mucin gene, MUC3.
• Associations of distinct variants of the intestinal mucin gene MUC3A with ulcerative colitis and Crohn's disease.
• Clinical comparison of branched-chain amino acid (l-Leucine, l-Isoleucine, l-Valine) granules and oral nutrition for hepatic insufficiency in patients with decompensated liver cirrhosis (LIV-EN study).
• Early prediction of sustained viral responder and non-responder during interferon and ribavirin combination therapy in chronic hepatitis C.
• Enzymatic activation of oleuropein: A protein crosslinker used as a chemical defense in the privet tree.
• Expression of DMRT genes in the gonads of Rana rugosa during sex determination.
• Expression of a novel type of classic cadherin, PB-cadherin in developing brain and limb buds.
• Fast screening of pesticide multiresidues in aqueous samples by dual stir bar sorptive extraction-thermal desorption-low thermal mass gas chromatography-mass spectrometry.
• Fucoidan prevents concanavalin A-induced liver injury through induction of endogenous IL-10 in mice.
• Genetic Effects of Radiation in Atomic-bomb Survivors and Their Children: Past, Present and Future.
• Gravitational and hormonal control in secondary xylem formation of Japanese flowering cherry.
• Heterozygous individuals bearing a founder mutation in the XPA DNA repair gene comprise nearly 1% of the Japanese population.
• Histological and physicochemical studies of hypercalcified primear lines in the laminar bone of young calves.
• Human recombinant BMP-2 in osseous reconstruction of simulated cleft palate defects.
• Identification of genes associated with the development of IgA nephropathy: genome-wide screening by SNP markers.
• Immunohistochemical properties of silent corticotroph adenoma and Cushing's disease.
• Macrophage inflammatory protein-1alpha plays a crucial role in concanavalin A-induced liver injury through induction of proinflammatory cytokines in mice.
• PCR-based landmark unique gene (PLUG) markers effectively assign homoeologous wheat genes to A, B and D genomes.
• Repeated administrations of concanavalin A induce Th1 to Th2 cytokine shift and tolerance against liver injury in mice.
• Requirement of mitogen-activated protein kinase for collagenase production by the fibronectin fragment in human articular chondrocytes in culture.
• Seroepidemiology of hepatitis B virus infection among children in Mongolia: results of a nationwide survey.
• Signal transduction pathways of calcitonin/calcitonin receptor regulating cytoskeletal organization and bone-resorbing activity of osteoclasts.
• The growth movement in the peduncle of Eichhornia crassipes II.
• Threshold for transitory diarrhea induced by ingestion of xylitol and lactitol in young male and female adults.
• Use of 11p15 mucins as prognostic factors in small adenocarcinoma of the lung.
• [BMP and osteoclastogenesis]