Detailed kinetics of immune responses to a new cell culture-derived smallpox vaccine in vaccinia-naïve adults.

Detailed kinetics of immune responses to a new cell culture-derived smallpox vaccine in vaccinia-naïve adults. Research Abstract Details 

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Detailed kinetics of immune responses to a new cell culture-derived smallpox vaccine in vaccinia-naïve adults. Abstract Text:

Sung-Han Kim,Su-Jin Choi,Wan Beom Park,Hong-Bin Kim,Nam-Joong Kim,Myoung-Don Oh,Kang-Won Choe,Sung-Han Kim,Su-Jin Choi,Wan Beom Park,Hong-Bin Kim,Nam-Joong Kim,Myoung-Don Oh,Kang-Won Choe,

The aim of the present study was to investigate the kinetics of humoral and cell-mediated immune responses to a new cell culture-derived smallpox vaccine (CJ-50300, CJ Corporation, South Korea) in 18 vaccinia-naïve volunteers. All subjects achieved positive humoral immune responses (plaque reduction neutralizing antibody assay) 28 days after vaccination, and cell-mediated immune responses (ELISPOT assay) 14 days after vaccination. Humoral immune responses increased up to 28 days after vaccination and were maintained up to 56 days after vaccination. In contrast, cell-mediated immune responses increased up to 14 days after vaccination and steadily decreased to 56 days after vaccination [Clinical Trial No. NCT 00336635].

Detailed kinetics of immune responses to a new cell culture-derived smallpox vaccine in vaccinia-naïve adults. Publishing Authors By Initials

SH Kim,SJ Choi,WB Park,HB Kim,NJ Kim,MD Oh,KW Choe,SH Kim,SJ Choi,WB Park,HB Kim,NJ Kim,MD Oh,KW Choe,

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Detailed kinetics of immune responses to a new cell culture-derived smallpox vaccine in vaccinia-naïve adults. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Vaccine

VOLUME: 25

Page Numbers: 6287-91

Journal Abbreviation: Vaccine

ISSN: 0264-410X

DAY: 11

MONTH: 06

YEAR: 2007

Detailed kinetics of immune responses to a new cell culture-derived smallpox vaccine in vaccinia-naïve adults. Information

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LANGUAGE: eng

NlmUniqueID: 8406899

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Grant and Affiliation Information for Detailed kinetics of immune responses to a new cell culture-derived smallpox vaccine in vaccinia-naïve adults.

AFFILIATION: Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.

Country: Netherlands

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MEDLINETA: Vaccine

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