Design, synthesis and X-ray structure of protein-ligand complexes: important insight into selectivity of memapsin 2 (beta-secretase) inhibitors.

Design, synthesis and X-ray structure of protein-ligand complexes: important insight into selectivity of memapsin 2 (beta-secretase) inhibitors. Research Abstract Details 

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Design, synthesis and X-ray structure of protein-ligand complexes: important insight into selectivity of memapsin 2 (beta-secretase) inhibitors. Abstract Text:

Arun K Ghosh,Nagaswamy Kumaragurubaran,Lin Hong,Hui Lei,Khaja Azhar Hussain,Chun-Feng Liu,Thippeswamy Devasamudram,Vajira Weerasena,Robert Turner,Gerald Koelsch,Geoffrey Bilcer,Jordan Tang,Arun K Ghosh,Nagaswamy Kumaragurubaran,Lin Hong,Hui Lei,Khaja Azhar Hussain,Chun-Feng Liu,Thippeswamy Devasamudram,Vajira Weerasena,Robert Turner,Gerald Koelsch,Geoffrey Bilcer,Jordan Tang,

Design, synthesis and X-ray structure of protein-ligand complexes: important insight into selectivity of memapsin 2 (beta-secretase) inhibitors. Publishing Authors By Initials

AK Ghosh,N Kumaragurubaran,L Hong,H Lei,KA Hussain,CF Liu,T Devasamudram,V Weerasena,R Turner,G Koelsch,G Bilcer,J Tang,AK Ghosh,N Kumaragurubaran,L Hong,H Lei,KA Hussain,CF Liu,T Devasamudram,V Weerasena,R Turner,G Koelsch,G Bilcer,J Tang,

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Design, synthesis and X-ray structure of protein-ligand complexes: important insight into selectivity of memapsin 2 (beta-secretase) inhibitors. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: Journal of the American Chemical Society

VOLUME: 128

Page Numbers: 5310-1

Journal Abbreviation: J. Am. Chem. Soc.

ISSN: 0002-7863

DAY: 26

MONTH: Apr

YEAR: 2006

Design, synthesis and X-ray structure of protein-ligand complexes: important insight into selectivity of memapsin 2 (beta-secretase) inhibitors. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 7503056

Design, synthesis and X-ray structure of protein-ligand complexes: important insight into selectivity of memapsin 2 (beta-secretase) inhibitors. Keywords Mesh Terms:

KEYWORDS: Proteins

MESH TERMS: chemistry

Chemical & Substance for Abstract: Design, synthesis and X-ray structure of protein-ligand complexes: important insight into selectivity of memapsin 2 (beta-secretase) inhibitors. Information

Substance Name: BACE1 protein, human

Registry Number: EC 3.4.23.46

Grant and Affiliation Information for Design, synthesis and X-ray structure of protein-ligand complexes: important insight into selectivity of memapsin 2 (beta-secretase) inhibitors.

AFFILIATION: Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, USA. akghosh@purdue.edu

Country: United States

AGENCY: United States NIA

GRANT: AG 18933

ACRONYM: AG

MEDLINETA: J Am Chem Soc

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