Design and analysis of experiments.

Design and analysis of experiments. Research Abstract Details 

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This chapter is primarily devoted to experiments that compare 2 treatments with respect to an outcome measure. Six design scenarios are discussed: (a) completely randomized designs (treatments are assigned completely at random); (b) randomized block designs (experimental units are subdivided into blocks of like subjects, with one subject in each block randomly assigned to each treatment); (c) stratified designs (subjects are categorized into subpopulations called strata, and within each stratum, a completely randomized design is conducted); (d) crossover designs (each subject gets both treatments, but order is completely at random); (e) 2 x 2 factorial designs [design can be in any of the formats (a)-(d) but there are 4 not 2 treatments representing 2 types of treatment interventions, each with 2 levels]; and (f) randomized designs with "random" effects. This is much like the stratified design, except there is only 1 sample, at least conceptually, from the strata. Examples might be litters of laboratory animals, surgical practices, or batches of a therapeutic agent. The desire is to make inferences about treatments in the population as a whole, not just in the strata that were actually sampled.

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Design and analysis of experiments. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: Methods in molecular biology (Clifton, N.J.)

VOLUME: 404

Page Numbers: 235-59

Journal Abbreviation: Methods Mol. Biol.

ISSN: 1064-3745

DAY: 2

MONTH: 05

YEAR: 2007

Design and analysis of experiments. Information

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LANGUAGE: eng

NlmUniqueID: 9214969

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Grant and Affiliation Information for Design and analysis of experiments.

AFFILIATION: Department of Health Policy/Epidemiology, University of Florida, Gainesville, FL, USA.

Country: United States

AGENCY: United States NCRR

GRANT: M01 RR00082

ACRONYM: RR

MEDLINETA: Methods Mol Biol

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