Depressor effect of closed-loop chip system in spontaneously hypertensive rats.

Depressor effect of closed-loop chip system in spontaneously hypertensive rats. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Depressor effect of closed-loop chip system in spontaneously hypertensive rats. Abstract Text:

Xing-Ya Gao,Xing-Lin Huang,Han-Jun Wang,Li-Min Zhou,Yao Xu,Wei Wang,Guo-Qing Zhu,Xing-Ya Gao,Xing-Lin Huang,Han-Jun Wang,Li-Min Zhou,Yao Xu,Wei Wang,Guo-Qing Zhu,

We previously reported that a closed-loop chip system was designed to decrease arterial pressure in normal rabbits and rats. In the present study, the depressor effects of the chip system were investigated in spontaneously hypertensive rats (SHR) and Wistar-Kyoto rats (WKY). The arterial pressure was recorded, sampled, operated and processed in the chip system. The chip system instantaneously controlled arterial pressure by stimulating the left aortic depressor nerve according to the feedback signals of arterial pressure. The closed-loop chip system effectively decreased mean arterial pressure (MAP) and heart rate (HR) in both SHR and WKY rats. It decreased the duration and the maximal MAP level of the pressor response evoked by either intravenous injection of phenylephrine or cutaneous nociceptive stimulation in SHR, but had no significant effect on the magnitude of the increase in MAP. Furthermore, the chip system significantly increased the baroreflex gain in SHR, but not in normal WKY rats. These results suggest that the closed-loop chip system effectively decreases the arterial pressure and increases baroreflex gain in SHR. The chip system does not abolish the arterial pressure responses to accidental pressor events, but decreases the duration and the maximal MAP level of the pressor responses.

Depressor effect of closed-loop chip system in spontaneously hypertensive rats. Publishing Authors By Initials

XY Gao,XL Huang,HJ Wang,LM Zhou,Y Xu,W Wang,GQ Zhu,XY Gao,XL Huang,HJ Wang,LM Zhou,Y Xu,W Wang,GQ Zhu,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Depressor effect of closed-loop chip system in spontaneously hypertensive rats. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Autonomic neuroscience : basic & clinical

VOLUME: 137

Page Numbers: 84-91

Journal Abbreviation:

ISSN: 1566-0702

DAY: 29

MONTH: 10

YEAR: 2007

Depressor effect of closed-loop chip system in spontaneously hypertensive rats. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 100909359

Depressor effect of closed-loop chip system in spontaneously hypertensive rats. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Depressor effect of closed-loop chip system in spontaneously hypertensive rats. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Depressor effect of closed-loop chip system in spontaneously hypertensive rats.

AFFILIATION: Department of Physiology, Nanjing Medical University, Nanjing 210029, China.

Country: Netherlands

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Auton Neurosci

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Depressor effect of closed-loop chip system in spontaneously hypertensive rats Related Publications

• Cell signaling by imidazoline-1 receptor candidate, IRAS, and the nischarin homologue.
• Cloning and expression of xeroderma pigmentosum complementation group A cDNA and the identification of its recombinant protein.
• Modification of glycosylation reduces microvilli on rat liver epithelial cells.
• [Aberrant neuronal expression of mitotic protein, tau and Bax in the rat brain after injection of Abeta(25-35) into the amygdala]
• [Application of expressed sequence tag (EST) in parasite genome research]
• [Clinical investigation of the correlation between blood concentration of lactic acid and tissue oxygenation in severely burned patients]
• [Combined detection of K-ras mutation and CA19-9 level in plasma of patients with pancreatic cancer]
• [Comparison of endoscopic irsection and vaporization for superficial bladder cancer]
• [Construction of the prokaryotic expression vector of MTB lhp gene and its expression]
• [Diagnosis and treatment of adrenal medullary hyperplasia (with report of 8 cases)]
• [Effects of Nomega-nitro-L-arginine on photoreceptor apoptosis in inherited retinal degeneration of RCS rats]
• [Effects of lamivudine on cirrhotic patients following chronic hepatitis B]
• [Effects of terrestrial input on the harmful algal bloom area--with aluminum as an example]
• [Experimental study on human reaction of determination and performance in virtual environment]
• [Expression of core-binding factor a1 by human skin fibroblasts induced in vitro]
• [Expression of some active peptides and extracellular matrix in the in vitro cultured tissue engineering skin]
• [Investigation of resection and reconstruction procedure of high-sacra tumors]
• [Mechanism of arsenic trioxide-induced apoptosis in hepatic blastoma cells HepG2]
• [Microzooplankton herbivory during red tide-frequent-occurrence period in spring in the East China Sea]
• [Regulative effects and significance of substance P on the expression of basic fibroblast growth factor of granulation tissue fibroblasts in vitro]
• [Role of NADH-cytochrome b(5) reductase in biosynthesis of thyroid hydrogen peroxide]
• [Study of specific targeting cytotoxicity mediated by anti-CD(3)/anti-CD(20) Diabody]
• [Study on gene mutation in 11 Chinese families with Hailey-Hailey disease]
• [Study on making pneumoconiosis model and method of lung lavage in rabbit]
• [Study on the mutation of human telomeric repeat binding factor 1 gene in malignant hematopoietic cell lines]
• [Successful management of sudden respiratory and heart arrest resulting from severe closed thoracoabdominal trauma: report of one case]
• [The expression and mechanism study of BMP in pleomorphic adenoma]
• [The mutation of anti-CD3 antibody (HIT3a) gene and its expression]
• [The prevention of primary liver cancer by selenium in high risk populations]
• kappa-Opioid receptor stimulation contributes to aortic artery dilation through activation of K(ATP) channel in the rats.