Deoxyribozymes as inhibitors of vascular smooth muscle cell growth.

Deoxyribozymes as inhibitors of vascular smooth muscle cell growth. Research Abstract Details 

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Deoxyribozymes as inhibitors of vascular smooth muscle cell growth. Abstract Text:

DNA enzymes, or DNAzymes, are all-DNA molecules with inherent catalytic activity that bind and cleave at their complementary sequence in the target mRNA through Watson-Crick base pairing. These agents have been successfully used to tease out the role the targeted gene plays in both cellular systems and in a variety of animal models. DNAzymes have the potential to serve as novel nucleic acid-based therapeutic agents in pathologies involving aberrant smooth muscle cell growth and a range of other disorders.

Deoxyribozymes as inhibitors of vascular smooth muscle cell growth. Publishing Authors By Initials

For similar cells: muscle cells: myocytes, smooth muscle research abstracts see: cells: muscle cells: myocytes, smooth muscle research

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Deoxyribozymes as inhibitors of vascular smooth muscle cell growth. Journal Published:

PUBLICATION TYPE: Review

Journal: Current pharmaceutical biotechnology

VOLUME: 5

Page Numbers: 337-9

Journal Abbreviation: Curr Pharm Biotechnol

ISSN: 1389-2010

DAY: 12

MONTH: Aug

YEAR: 2004

Deoxyribozymes as inhibitors of vascular smooth muscle cell growth. Information

Number of References: 19

LANGUAGE: eng

NlmUniqueID: 100960530

Deoxyribozymes as inhibitors of vascular smooth muscle cell growth. Keywords Mesh Terms:

KEYWORDS: Myocytes, Smooth Muscle

MESH TERMS: physiology

Chemical & Substance for Abstract: Deoxyribozymes as inhibitors of vascular smooth muscle cell growth. Information

Substance Name: DNA, Catalytic

Registry Number: 0

Grant and Affiliation Information for Deoxyribozymes as inhibitors of vascular smooth muscle cell growth.

AFFILIATION: Centre for Vascular Research, University of New South Wales and Department of Haematology, The Prince of Wales Hospital, Sydney, Australia. L.Khachigian@unsw.edu.au

Country: Netherlands

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MEDLINETA: Curr Pharm Biotechnol

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