Deoxyribonucleoside phosphoramidites.

Deoxyribonucleoside phosphoramidites. Research Abstract Details 

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Deoxyribonucleoside phosphoramidites. Abstract Text:

The detailed preparation of deoxyribonucleoside phosphoramidites bearing a 4-[N-methyl-N-(2,2,2-trifluoroacetyl)amino]butyl group for P(III) protection is presented. The use of this group circumvents nucleobase alkylation during oligonucleotide deprotection. Two syntheses of phosphoramidites starting from either a phosphordichloridite precursor or a bis-(N,N-diisopropylamino)chlorophosphine intermediate are described for the phosphinylation of suitably protected deoxyribonucleosides.

Deoxyribonucleoside phosphoramidites. Publishing Authors By Initials

For similar organic chemicals: organophosphorus compounds research abstracts see: organic chemicals: organophosphorus compounds research

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MEDLINE DATE:

Deoxyribonucleoside phosphoramidites. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Current protocols in nucleic acid chemistry / edit

VOLUME: Chapter 2

Page Numbers: Unit 2.7

Journal Abbreviation:

ISSN: 1934-9289

DAY: 8

MONTH: May

YEAR: 2001

Deoxyribonucleoside phosphoramidites. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 101287865

Deoxyribonucleoside phosphoramidites. Keywords Mesh Terms:

KEYWORDS: Organophosphorus Compounds

MESH TERMS: chemistry

Chemical & Substance for Abstract: Deoxyribonucleoside phosphoramidites. Information

Substance Name: 1-Butanol

Registry Number: 71-36-3

Grant and Affiliation Information for Deoxyribonucleoside phosphoramidites.

AFFILIATION: Food and Drug Administration, Bethesda, Maryland, USA.

Country: United States

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MEDLINETA: Curr Protoc Nucleic Acid Chem

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