Demonstration of two new endogenous "benzodiazepine-like" compounds from brain.

Demonstration of two new endogenous "benzodiazepine-like" compounds from brain. Research Abstract Details 

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Demonstration of two new endogenous "benzodiazepine-like" compounds from brain. Abstract Text:

The recent report that purines are competitive inhibitors of specific [3H] diazepam binding to brain membranes has prompted further work concerning the characterization of possible endogenous ligands for the benzodiazepine receptor. In this report, two previously undescribed fractions capable of apparent competitive inhibition of [3H] diazepam binding are reported. Both factors are heat stable and resistant to proteolytic degradation. The larger factor (approximately 700 to 30,000 daltons) is present only in brain and pituitary. The smaller factor (500 to 600 daltons) is found in pituitary, liver, and muscle, but the highest levels are found in brain.

Demonstration of two new endogenous "benzodiazepine-like" compounds from brain. Publishing Authors By Initials

For similar proteins: receptors, drug research abstracts see: proteins: receptors, drug research

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Demonstration of two new endogenous "benzodiazepine-like" compounds from brain. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Psychiatry research

VOLUME: 1

Page Numbers: 121-30

Journal Abbreviation: Psychiatry Res

ISSN: 0165-1781

DAY: 17

MONTH: Oct

YEAR: 1979

Demonstration of two new endogenous "benzodiazepine-like" compounds from brain. Information

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LANGUAGE: eng

NlmUniqueID: 7911385

Demonstration of two new endogenous "benzodiazepine-like" compounds from brain. Keywords Mesh Terms:

KEYWORDS: Receptors, Drug

MESH TERMS: analysis

Chemical & Substance for Abstract: Demonstration of two new endogenous "benzodiazepine-like" compounds from brain. Information

Substance Name: Receptors, Drug

Registry Number: 0

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Country: NETHERLANDS

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MEDLINETA: Psychiatry Res

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