Demonstration of autoantibodies against ACTH in serum from a patient with cancer of unknown origin.

Demonstration of autoantibodies against ACTH in serum from a patient with cancer of unknown origin. Research Abstract Details 

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Demonstration of autoantibodies against ACTH in serum from a patient with cancer of unknown origin. Abstract Text:

We report the presence of autoantibodies against ACTH in plasma from a 46 year old man with poorly differentiated adenocarcinoma of unknown origin. There was no evidence of Cushing's syndrome. By radioimmunoassay and immunocytochemical technique the antibodies were found to possess specificity against the 13-24 aminoacid sequence of ACTH. This sequence includes the biologically active site. On the basis of our findings it is discussed whether the presence of the autoantibodies could reflect a fundamental immunological disturbance primarily or secondarily related to cancer.

Demonstration of autoantibodies against ACTH in serum from a patient with cancer of unknown origin. Publishing Authors By Initials

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Demonstration of autoantibodies against ACTH in serum from a patient with cancer of unknown origin. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Acta pathologica, microbiologica, et immunologica

VOLUME: 91

Page Numbers: 489-91

Journal Abbreviation:

ISSN: 0108-0164

DAY: 26

MONTH: Nov

YEAR: 1983

Demonstration of autoantibodies against ACTH in serum from a patient with cancer of unknown origin. Information

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LANGUAGE: eng

NlmUniqueID: 8206622

Demonstration of autoantibodies against ACTH in serum from a patient with cancer of unknown origin. Keywords Mesh Terms:

KEYWORDS: Male

MESH TERMS: analysis

Chemical & Substance for Abstract: Demonstration of autoantibodies against ACTH in serum from a patient with cancer of unknown origin. Information

Substance Name: Adrenocorticotropic Hormone

Registry Number: 9002-60-2

Grant and Affiliation Information for Demonstration of autoantibodies against ACTH in serum from a patient with cancer of unknown origin.

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Country: DENMARK

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MEDLINETA: Acta Pathol Microbiol Immunol

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