Defective luteal phase--measurement and evaluation of the ovarian hormone before and during cyclofenil (bis-P-acetoxphenyl) cyclo-hexylidenemethane (Compound 6066) treatment.

Defective luteal phase--measurement and evaluation of the ovarian hormone before and during cyclofenil (bis-P-acetoxphenyl) cyclo-hexylidenemethane (Compound 6066) treatment. Research Abstract Details 

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Defective luteal phase--measurement and evaluation of the ovarian hormone before and during cyclofenil (bis-P-acetoxphenyl) cyclo-hexylidenemethane (Compound 6066) treatment. Abstract Text:

The nature of defective luteal phase (DLP) was investigated by the measurement and evaluation of the ovarian hormone before and during Cyclofenil (bis-p-acetoxphenyl) cyclo-hexylidenemethane treatment. Total urinary estrogens and plasma progesterone were measured in 50 infertile patients with DLP. Prior to treatment these patients revealed wide variations in their urinary estrogen pattern while plasma progesterone was uniformly low. Treatment results were dependent on the dose of Cyclofenil and on the baseline estrogen configuration of the patient. The pregnancy rate was 28%. The results indicated that follicular dysmaturity precedes luteal insufficiency in the majority of cases. Therefore, treatment should be aimed at correcting the hormonal imbalance both at hypothalamico pituitary axis level and at the ovarian level rather than simple substitution therapy. Both of these qualities are present in Cyclofenil.

Defective luteal phase--measurement and evaluation of the ovarian hormone before and during cyclofenil (bis-P-acetoxphenyl) cyclo-hexylidenemethane (Compound 6066) treatment. Publishing Authors By Initials

For similar polycyclic compounds: steroids: pregnanes: pregnenes: pregnenediones: progesterone research abstracts see: polycyclic compounds: steroids: pregnanes: pregnenes: pregnenediones: progesterone research

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Defective luteal phase--measurement and evaluation of the ovarian hormone before and during cyclofenil (bis-P-acetoxphenyl) cyclo-hexylidenemethane (Compound 6066) treatment. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: The West Indian medical journal

VOLUME: 25

Page Numbers: 107-20

Journal Abbreviation: West Indian Med J

ISSN: 0043-3144

DAY: 10

MONTH: Jun

YEAR: 1976

Defective luteal phase--measurement and evaluation of the ovarian hormone before and during cyclofenil (bis-P-acetoxphenyl) cyclo-hexylidenemethane (Compound 6066) treatment. Information

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LANGUAGE: eng

NlmUniqueID: 417410

Defective luteal phase--measurement and evaluation of the ovarian hormone before and during cyclofenil (bis-P-acetoxphenyl) cyclo-hexylidenemethane (Compound 6066) treatment. Keywords Mesh Terms:

KEYWORDS: Progesterone

MESH TERMS: blood

Chemical & Substance for Abstract: Defective luteal phase--measurement and evaluation of the ovarian hormone before and during cyclofenil (bis-P-acetoxphenyl) cyclo-hexylidenemethane (Compound 6066) treatment. Information

Substance Name: Progesterone

Registry Number: 57-83-0

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Country: JAMAICA

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MEDLINETA: West Indian Med J

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