Decreased Lempel-Ziv complexity in Alzheimer's disease patients' magnetoencephalograms.

Decreased Lempel-Ziv complexity in Alzheimer's disease patients' magnetoencephalograms. Research Abstract Details 

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Decreased Lempel-Ziv complexity in Alzheimer's disease patients' magnetoencephalograms. Abstract Text:

Carlos Gomez,Roberto Hornero,Daniel Abasolo,Miguel Lopez,Alberto Fernandez,

The aim of the present research is to study the magnetoencephalogram (MEG) background activity in patients with Alzheimer's disease (AD) using the Lempel-Ziv (LZ) complexity. We recorded the MEG with a 148-channel whole-head magnetometer (MAGNES 2500 WH, 4D Neuroimaging) in 10 patients with probable AD and 10 age-matched control subjects, during five minutes. Artefact-free epochs were selected for the non-linear analysis. In all MEG channels, the AD patients had lower complexity than control subjects. In 77 of them the differences were statistically significant (p < 0.01). These preliminary results suggest that cognitive dysfunction in AD is associated with a decreased complexity in certain regions of the brain.

Decreased Lempel-Ziv complexity in Alzheimer's disease patients' magnetoencephalograms. Publishing Authors By Initials

C Gomez,R Hornero,D Abasolo,M Lopez,A Fernandez,

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Decreased Lempel-Ziv complexity in Alzheimer's disease patients' magnetoencephalograms. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Conference proceedings : ... Annual International

VOLUME: 5

Page Numbers: 4514-7

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ISSN: 1557-170X

DAY: 6

MONTH: 02

YEAR: 2005

Decreased Lempel-Ziv complexity in Alzheimer's disease patients' magnetoencephalograms. Information

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LANGUAGE: eng

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AFFILIATION: E.T.S. Ingenieros de Telecomunicacion, Universidad de Valladolid, Spain. Email: cgompen@ribera.tel.uva.es.

Country: United States

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