Decreased bone mineral density with off-label use of tenofovir in children and adolescents infected with human immunodeficiency virus.

Decreased bone mineral density with off-label use of tenofovir in children and adolescents infected with human immunodeficiency virus. Research Abstract Details 

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Decreased bone mineral density with off-label use of tenofovir in children and adolescents infected with human immunodeficiency virus. Abstract Text:

Julia B Purdy,Rachel I Gafni,James C Reynolds,Steven Zeichner,Rohan Hazra,

5 of 6 children infected with human immunodeficiency virus (HIV) receiving Tenofovir disoproxil fumarate (TDF) experienced absolute decreases in bone mineral density (BMD). 2 pre-pubertal subjects experienced >6% BMD decreases. 1 subject was the smallest child and experienced a 27% decrease, necessitating withdrawal of TDF. Subsequently, her BMD recovered. Monitoring of children infected with HIV who require treatment with TDF is warranted.

Decreased bone mineral density with off-label use of tenofovir in children and adolescents infected with human immunodeficiency virus. Publishing Authors By Initials

JB Purdy,RI Gafni,JC Reynolds,S Zeichner,R Hazra,

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Decreased bone mineral density with off-label use of tenofovir in children and adolescents infected with human immunodeficiency virus. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: The Journal of pediatrics

VOLUME: 152

Page Numbers: 582-4

Journal Abbreviation: J. Pediatr.

ISSN: 1097-6833

DAY: 18

MONTH: Apr

YEAR: 2008

Decreased bone mineral density with off-label use of tenofovir in children and adolescents infected with human immunodeficiency virus. Information

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LANGUAGE: eng

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Grant and Affiliation Information for Decreased bone mineral density with off-label use of tenofovir in children and adolescents infected with human immunodeficiency virus.

AFFILIATION: HIV and AIDS Malignancy Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD.

Country: United States

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MEDLINETA: J Pediatr

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