De novo formal synthesis of (-)-virginiamycin M2 via the asymmetric hydration of dienoates.

De novo formal synthesis of (-)-virginiamycin M2 via the asymmetric hydration of dienoates. Research Abstract Details 

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De novo formal synthesis of (-)-virginiamycin M2 via the asymmetric hydration of dienoates. Abstract Text:

Matthew S Mortensen,Joshua M Osbourn,George A O'Doherty,

A de novo approach to the formal total synthesis of the macrolide natural product (-)-virginiamycin M2 has been achieved via a convergent approach. The absolute and relative stereochemistry of the nonpeptide portion of (-)-virginiamycin M2 was introduced by two Sharpless asymmetric dihydroxylation reactions.

De novo formal synthesis of (-)-virginiamycin M2 via the asymmetric hydration of dienoates. Publishing Authors By Initials

MS Mortensen,JM Osbourn,GA O'Doherty,

For similar polycyclic compounds: macrocyclic compounds: peptides, cyclic: streptogramins: virginiamycin research abstracts see: polycyclic compounds: macrocyclic compounds: peptides, cyclic: streptogramins: virginiamycin research

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De novo formal synthesis of (-)-virginiamycin M2 via the asymmetric hydration of dienoates. Journal Published:

PUBLICATION TYPE: Research Support, U.S. Gov't,

Journal: Organic letters

VOLUME: 9

Page Numbers: 3105-8

Journal Abbreviation: Org. Lett.

ISSN: 1523-7060

DAY: 3

MONTH: 07

YEAR: 2007

De novo formal synthesis of (-)-virginiamycin M2 via the asymmetric hydration of dienoates. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 100890393

De novo formal synthesis of (-)-virginiamycin M2 via the asymmetric hydration of dienoates. Keywords Mesh Terms:

KEYWORDS: Virginiamycin

MESH TERMS: chemistry

Chemical & Substance for Abstract: De novo formal synthesis of (-)-virginiamycin M2 via the asymmetric hydration of dienoates. Information

Substance Name: Virginiamycin

Registry Number: 11006-76-1

Grant and Affiliation Information for De novo formal synthesis of (-)-virginiamycin M2 via the asymmetric hydration of dienoates.

AFFILIATION: Department of Chemistry, West Virginia University, Morgantown, West Virginia 26506, USA.

Country: United States

AGENCY: United States NIGMS

GRANT: GM63150

ACRONYM: GM

MEDLINETA: Org Lett

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