De novo asymmetric syntheses of muricatacin and its analogues via dihydroxylation of dienoates.

De novo asymmetric syntheses of muricatacin and its analogues via dihydroxylation of dienoates. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

De novo asymmetric syntheses of muricatacin and its analogues via dihydroxylation of dienoates. Abstract Text:

Md Moinuddin Ahmed,Hu Cui,George A O'Doherty,

A short and highly efficient route to both enantiomers of muricatacin as well as the C-5-epimer has been developed. The key to the overall transformation is the highly regio- and enantioselective Sharpless asymmetric dihydroxylation of an (E,Z)-dienoate. The highly efficient stereoselective synthesis prepares (-)-muricatacin in seven steps and 66% overall yield.

De novo asymmetric syntheses of muricatacin and its analogues via dihydroxylation of dienoates. Publishing Authors By Initials

MM Ahmed,H Cui,GA O'Doherty,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

De novo asymmetric syntheses of muricatacin and its analogues via dihydroxylation of dienoates. Journal Published:

PUBLICATION TYPE: Research Support, U.S. Gov't,

Journal: The Journal of organic chemistry

VOLUME: 71

Page Numbers: 6686-9

Journal Abbreviation:

ISSN: 0022-3263

DAY: 18

MONTH: Aug

YEAR: 2006

De novo asymmetric syntheses of muricatacin and its analogues via dihydroxylation of dienoates. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 2985193

De novo asymmetric syntheses of muricatacin and its analogues via dihydroxylation of dienoates. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: De novo asymmetric syntheses of muricatacin and its analogues via dihydroxylation of dienoates. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for De novo asymmetric syntheses of muricatacin and its analogues via dihydroxylation of dienoates.

AFFILIATION: Department of Chemistry, West Virginia University, Morgantown, West Virginia 26506, USA.

Country: United States

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: J Org Chem

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

De novo asymmetric syntheses of muricatacin and its analogues via dihydroxylation of dienoates Related Publications

• A moderate increase in carnitine palmitoyltransferase 1a activity is sufficient to substantially reduce hepatic triglyceride levels.
• A new hearing test applicable to the crying newborn infant.
• A palladium-catalyzed glycosylation reaction: the de novo synthesis of natural and unnatural glycosides.
• A stereoselective synthesis of digitoxin and digitoxigen mono- and bisdigitoxoside from digitoxigenin via a palladium-catalyzed glycosylation.
• Addition of deoxynucleosides enhances human immunodeficiency virus type 1 integration and 2LTR formation in resting CD4+ T cells.
• Anterior tibial artery pseudoaneurysm in a patient with hemophilia: a complication of ankle arthroscopy.
• De Novo Asymmetric Synthesis of 8a-epi-Swainsonine.
• De novo approach to 2-deoxy-beta-glycosides: asymmetric syntheses of digoxose and digitoxin.
• De novo asymmetric syntheses of SL0101 and its analogues via a palladium-catalyzed glycosylation.
• De novo asymmetric syntheses of muricatacin and its analogues via dihydroxylation of dienoates.
• De novo asymmetric synthesis of milbemycin beta3 via an iterative asymmetric hydration approach.
• De novo asymmetric synthesis of the anthrax tetrasaccharide by a palladium-catalyzed glycosylation reaction.
• De novo formal synthesis of (-)-apicularen A via an iterative asymmetric hydration sequence.
• De novo formal synthesis of (-)-virginiamycin M2 via the asymmetric hydration of dienoates.
• De novo synthesis of 2-substituted syn-1,3-diols via an iterative asymmetric hydration strategy.
• De novo synthesis of oligosaccharides using a palladium-catalyzed glycosylation reaction.
• Determining the neural substrates of goal-directed learning in the human brain.
• Glucuronidase and lipids in wallerian degeneration.
• HIV-1 integrates into resting CD4+ T cells even at low inoculums as demonstrated with an improved assay for HIV-1 integration.
• Imaging neuroendocrine tumours with radionuclide techniques.
• Inhibition or deletion of the lipopolysaccharide receptor Toll-like receptor-4 confers partial protection against lipid-induced insulin resistance in rodent skeletal muscle.
• Lights, camembert, action! The role of human orbitofrontal cortex in encoding stimuli, rewards, and choices.
• Positron emission tomography and the orthopaedic surgeon.
• Preparation and stability of a radioiodinated pentamidine isethionate analog.
• Reinforcement learning signals in the human striatum distinguish learners from nonlearners during reward-based decision making.
• Synthesis of aza-analogues of the glycosylated tyrosine portion of mannopeptimycin-E.
• The de novo synthesis of oligosaccharides: application to the medicinal chemistry SAR-study of digitoxin.
• The influence of manure composition on emissions of odour and ammonia from finishing pigs fed different concentrations of dietary crude protein.
• [18F]2-fluoro-2-deoxy-D-glucose positron emission tomography (FDG PET) as a diagnostic tool for neurofibromatosis 1 (NF1) associated malignant peripheral nerve sheath tumours (MPNSTs): a long-term clinical study.
• [Sinterloy technic. Ceramic framework of metallic powder]