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DB-PABP: a database of polyanion-binding proteins.

DB-PABP: a database of polyanion-binding proteins. Research Abstract Details 

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  • DB-PABP: a database of polyanion-binding proteins. Abstract Text:

    jianwen fangJianwen Fang,yinghua dongYinghua Dong,nazila salamat-millerNazila Salamat-Miller,c russell middaughC Russell Middaugh,jianwen fangJianwen Fang,yinghua dongYinghua Dong,nazila salamat-millerNazila Salamat-Miller,c russell middaughC Russell Middaugh,jianwen fangJianwen Fang,yinghua dongYinghua Dong,nazila salamat-millerNazila Salamat-Miller,c russell middaughC Russell Middaugh,jianwen fangJianwen Fang,yinghua dongYinghua Dong,nazila salamat-millerNazila Salamat-Miller,c russell middaughC Russell Middaugh,

    The interactions between polyanions (PAs) and polyanion-binding proteins (PABPs) have been found to play significant roles in many essential biological processes including intracellular organization, transport and protein folding. Furthermore, many neurodegenerative disease-related proteins are PABPs. Thus, a better understanding of PA/PABP interactions may not only enhance our understandings of biological systems but also provide new clues to these deadly diseases. The literature in this field is widely scattered, suggesting the need for a comprehensive and searchable database of PABPs. The DB-PABP is a comprehensive, manually curated and searchable database of experimentally characterized PABPs. It is freely available and can be accessed online at http://pabp.bcf.ku.edu/DB_PABP/. The DB-PABP was implemented as a MySQL relational database. An interactive web interface was created using Java Server Pages (JSP). The search page of the database is organized into a main search form and a section for utilities. The main search form enables custom searches via four menus: protein names, polyanion names, the source species of the proteins and the methods used to discover the interactions. Available utilities include a commonality matrix, a function of listing PABPs by the number of interacting polyanions and a string search for author surnames. The DB-PABP is maintained at the University of Kansas. We encourage users to provide feedback and submit new data and references.

    DB-PABP: a database of polyanion-binding proteins. Publishing Authors By Initials

    j fangJ Fang,y dongY Dong,n salamat-millerN Salamat-Miller,c russell middaughC Russell Middaugh,j fangJ Fang,y dongY Dong,n salamat-millerN Salamat-Miller,c russell middaughC Russell Middaugh,j fangJ Fang,y dongY Dong,n salamat-millerN Salamat-Miller,c russell middaughC Russell Middaugh,j fangJ Fang,y dongY Dong,n salamat-millerN Salamat-Miller,cr middaughCR Middaugh,

    For similar information science: computing methodologies: software: user-computer interface research abstracts see: information science: computing methodologies: software: user-computer interface research

    PUBMED ID PMID:

    MEDLINE DATE:

    DB-PABP: a database of polyanion-binding proteins. Journal Published:

    PUBLICATION TYPE: Research Support, Non-U.S. Gov

    Journal: Nucleic acids research

    VOLUME: 36

    Page Numbers: D303-6

    Journal Abbreviation: Nucleic Acids Res.

    ISSN: 1362-4962

    DAY: 4

    MONTH: 10

    YEAR: 2007

    DB-PABP: a database of polyanion-binding proteins. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 411011

    DB-PABP: a database of polyanion-binding proteins. Keywords Mesh Terms:

    KEYWORDS: User-Computer Interface

    MESH TERMS: metabolism

    Chemical & Substance for Abstract: DB-PABP: a database of polyanion-binding proteins. Information

    Substance Name: Heparitin Sulfate

    Registry Number: 9050-30-0

    Grant and Affiliation Information for DB-PABP: a database of polyanion-binding proteins.

    AFFILIATION: Bioinformatics Core Facility, Information and Telecommunication Technology Center, University of Kansas, Lawrence, KS 66047, USA.

    Country: England

    England Research PublicationEngland Research Publication

    AGENCY: United States NCRR

    GRANT: P20 RR016475

    ACRONYM: RR

    MEDLINETA: Nucleic Acids Res

    REFSOURCE:

    DATABASENAME:

    ACCESSION NUMBER:

    Number Hits: 0

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