Cytotoxic sesquiterpene lactones from Eupatorium lindleyanum.

Cytotoxic sesquiterpene lactones from Eupatorium lindleyanum. Research Abstract Details 

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Cytotoxic sesquiterpene lactones from Eupatorium lindleyanum. Abstract Text:

N-Y Yang,S-H Qian,J-A Duan,P Li,L-J Tian,N-Y Yang,S-H Qian,J-A Duan,P Li,L-J Tian,

Three new germacrane sesquiterpenes, eupalinolides C-E (1-3), along with three known germacrane sesquiterpenes, eupalinolide A (4), eupalinolide B (5), and 3beta-acetoxy-8beta-(4'-hydroxytigloyloxy)-14-hydroxycostunolide (6), were isolated from Eupatorium lindleyanum. They were tested for cytotoxicity against A-549, BGC-823, SMMC-7721, and HL-60 tumour cell lines. The results showed that these compounds demonstrated potent cytotoxicity. The structures of the compounds were elucidated by means of (1)H and (13)C NMR spectroscopic analysis, including 2D NMR experiments.

Cytotoxic sesquiterpene lactones from Eupatorium lindleyanum. Publishing Authors By Initials

NY Yang,SH Qian,JA Duan,P Li,LJ Tian,NY Yang,SH Qian,JA Duan,P Li,LJ Tian,

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Cytotoxic sesquiterpene lactones from Eupatorium lindleyanum. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Journal of Asian natural products research

VOLUME: 9

Page Numbers: 339-45

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ISSN: 1028-6020

DAY: 6

MONTH: 07

YEAR: 2007

Cytotoxic sesquiterpene lactones from Eupatorium lindleyanum. Information

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LANGUAGE: eng

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Grant and Affiliation Information for Cytotoxic sesquiterpene lactones from Eupatorium lindleyanum.

AFFILIATION: Department of Pharmacognosy, China Pharmaceutical University, Nanjing 210038, China.

Country: England

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MEDLINETA: J Asian Nat Prod Res

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