Current trends in biocompatibility testing.

Current trends in biocompatibility testing. Research Abstract Details 

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Current trends in biocompatibility testing. Abstract Text:

C J Kirkpatrick,F Bittinger,M Wagner,H Köhler,T G van Kooten,C L Klein,M Otto,

Biocompatibility remains the central theme for biomaterials applications in medicine. It is generally accepted that this term means not only absence of a cytotoxic effect but also positive effects in the sense of biofunctionality, i.e. promotion of biological processes which further the intended aim of the application of a biomaterial. The national and international standards for testing regimes represent a lowest common denominator for such applications and do not necessarily ensure that optimal function will be achieved. The authors' thesis is that biocompatibility testing has scope for extensive development with respect to biofunctionality. The present paper reviews current trends in the in vitro aspects of biocompatibility testing. As well as a critical appraisal of the recent literature, future trends are also stressed, which the authors regard as essential for a meaningful integration of a modern biological approach into new developments in the material sciences. These include the application of modern techniques of cell and molecular biology, the concepts of tissue remodelling, hybrid organ development and encapsulated cell technology.

Current trends in biocompatibility testing. Publishing Authors By Initials

CJ Kirkpatrick,F Bittinger,M Wagner,H Köhler,TG van Kooten,CL Klein,M Otto,

For similar health occupations: allied health occupations: technology, medical research abstracts see: health occupations: allied health occupations: technology, medical research

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Current trends in biocompatibility testing. Journal Published:

PUBLICATION TYPE: Review

Journal: Proceedings of the Institution of Mechanical Engin

VOLUME: 212

Page Numbers: 75-84

Journal Abbreviation:

ISSN: 0954-4119

DAY: 21

MONTH: 02

YEAR: 1998

Current trends in biocompatibility testing. Information

Number of References: 87

LANGUAGE: eng

NlmUniqueID: 8908934

Current trends in biocompatibility testing. Keywords Mesh Terms:

KEYWORDS: Technology, Medical

MESH TERMS: trends

Chemical & Substance for Abstract: Current trends in biocompatibility testing. Information

Substance Name: Biocompatible Materials

Registry Number: 0

Grant and Affiliation Information for Current trends in biocompatibility testing.

AFFILIATION: Institute of Pathology, Johannes Gutenberg University, Mainz, Germany.

Country: ENGLAND

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MEDLINETA: Proc Inst Mech Eng [H]

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