Current status of virtual screening as analysed by target class.

Current status of virtual screening as analysed by target class. Research Abstract Details 

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Current status of virtual screening as analysed by target class. Abstract Text:

In silico virtual screening for drug discovery has become a hot topic in medicinal chemistry research during the last 5 years, growing from a largely academic pursuit concerned principally with validating the methods used, to a major early-stage technique for lead discovery in the pharmaceutical industry. In this review we highlight a few recent successes in ligand docking associated with virtual screening, paying particular attention to four major target classes of pharmaceutical interest (G Protein-Coupled receptors, nuclear hormone receptors, kinases, proteases). We also discuss some emerging trends in the field, some common limitations, and how they are being overcome.

Current status of virtual screening as analysed by target class. Publishing Authors By Initials

For similar investigative techniques: technology, pharmaceutical research abstracts see: investigative techniques: technology, pharmaceutical research

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Current status of virtual screening as analysed by target class. Journal Published:

PUBLICATION TYPE: Review

Journal: Medicinal chemistry (Sh?riqah (United Arab Emirate

VOLUME: 2

Page Numbers: 89-112

Journal Abbreviation:

ISSN: 1573-4064

DAY: 26

MONTH: Jan

YEAR: 2006

Current status of virtual screening as analysed by target class. Information

Number of References: 244

LANGUAGE: eng

NlmUniqueID: 101240303

Current status of virtual screening as analysed by target class. Keywords Mesh Terms:

KEYWORDS: Technology, Pharmaceutical

MESH TERMS: trends

Chemical & Substance for Abstract: Current status of virtual screening as analysed by target class. Information

Substance Name: Peptide Hydrolases

Registry Number: EC 3.4.-

Grant and Affiliation Information for Current status of virtual screening as analysed by target class.

AFFILIATION: Centre for Drug Design and Development, Institute for Molecular Bioscience, University of Queensland, Brisbane, Qld 4072, Australia. m.stoermer@imb.uq.edu.au

Country: United Arab Emirates

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MEDLINETA: Med Chem

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