Current development in microfluidic immunosensing chip.

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Current development in microfluidic immunosensing chip. Abstract Text:

This review accounts for the current development in microfluidic immunosensing chips. The basic knowledge of immunoassay in relation to its microfluidic material substrate, fluid handling and detection mode are briefly discussed. Here, we mainly focused on the surface modification, antibody immobilization, detection, signal enhancement and multiple analyte sensing. Some of the clinically important currently implemented on the microfluidic immunoassay chips are C-reactive protein (CRP), prostate specific antigen (PSA), ferritin, vascular endothelial growth factor (VEGF), myoglobin (Myo), cardiac troponin T (cTnT), cardiac troponin I (cTnI), and creatine kinase-cardiac muscle isoform (CK-MB). The emerging microfludic immunosensor technology may be a promising prospect that can propel the improvement of clinical and medical diagnosis.

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Current development in microfluidic immunosensing chip. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Analytica chimica acta

VOLUME: 611

Page Numbers: 17-30

Journal Abbreviation: Anal. Chim. Acta

ISSN: 1873-4324

DAY: 5

MONTH: 02

YEAR: 2008

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LANGUAGE: eng

NlmUniqueID: 370534

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Grant and Affiliation Information for Current development in microfluidic immunosensing chip.

AFFILIATION: Graduate School of Material Science, University of Hyogo, 3-2-1 Kouto, Kamigori-cho, Ako-gun, Hyogo 678-1297 Japan.

Country: Netherlands

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MEDLINETA: Anal Chim Acta

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