CT colonography of colorectal polyps: a metaanalysis.

CT colonography of colorectal polyps: a metaanalysis. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

CT colonography of colorectal polyps: a metaanalysis. Abstract Text:

Jacob Sosna,Martina M Morrin,Jonathan B Kruskal,Philip T Lavin,Max P Rosen,Vassilios Raptopoulos,

OBJECTIVE: For proper evaluation of the accuracy of CT colonography, prospective multiinstitutional trials would be ideal. Until these trials are available, data can be collectively analyzed. The purpose of this study is to use metaanalysis to assess the reported accuracy of CT colonography compared with conventional colonoscopy for detecting colorectal polyps. MATERIALS AND METHODS: Articles comparing CT colonography and conventional colonoscopy were identified, and a standardized form was used to extract relevant study data. Fisher's exact test and the Mantel-Haenszel test were used for pooling of data. A 95% confidence interval (CI) was selected to determine sensitivity and specificity, and the Kruskal-Wallis exact test was used to identify trends relating to polyp size. Meta-analysis methods were used to test strength of results. Comparisons were made for the percentage of polyps detected grouped by size (> or = 10 mm, 6-9 mm, < or = 5 mm) and the percentage of patients identified who had polyps of the same size. RESULTS: Fourteen studies fulfilled all the study inclusion criteria and gave a total of 1,324 patients and 1,411 polyps. The pooled per-patient sensitivity for polyps 10 mm or larger was (sensitivity [95% CI]) 0.88 (0.84-0.93), for polyps 6-9 mm it was 0.84 (0.80-0.89), and for polyps 5 mm or smaller it was 0.65 (0.57-0.73). The pooled per-polyp sensitivity for polyps 10 mm or larger was 0.81 (0.76-0.85), for polyps 6-9 mm it was 0.62 (0.58-0.67), and for polyps 5 mm or smaller it was 0.43 (0.39-0.47). Sensitivity for detection of polyps increased as the polyp size increased (p < 0.00005). The pooled overall specificity for detection of polyps larger than 10 mm was 0.95 (0.94-0.97). CONCLUSION: The specificity and sensitivity of CT colonography are high for polyps larger than 10 mm.

CT colonography of colorectal polyps: a metaanalysis. Publishing Authors By Initials

J Sosna,MM Morrin,JB Kruskal,PT Lavin,MP Rosen,V Raptopoulos,

For similar investigative techniques: epidemiologic methods: statistics as topic: sensitivity and specificity research abstracts see: investigative techniques: epidemiologic methods: statistics as topic: sensitivity and specificity research

PUBMED ID PMID:

MEDLINE DATE:

CT colonography of colorectal polyps: a metaanalysis. Journal Published:

PUBLICATION TYPE: Meta-Analysis

Journal: AJR. American journal of roentgenology

VOLUME: 181

Page Numbers: 1593-8

Journal Abbreviation:

ISSN: 0361-803X

DAY: 15

MONTH: Dec

YEAR: 2003

CT colonography of colorectal polyps: a metaanalysis. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 7708173

CT colonography of colorectal polyps: a metaanalysis. Keywords Mesh Terms:

KEYWORDS: Sensitivity and Specificity

MESH TERMS: radiography

Chemical & Substance for Abstract: CT colonography of colorectal polyps: a metaanalysis. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for CT colonography of colorectal polyps: a metaanalysis.

AFFILIATION: Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave., Boston, MA 02215, USA. jsosna@bidmc.harvard.edu

Country: United States

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: AJR Am J Roentgenol

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

CT colonography of colorectal polyps: a metaanalysis Related Publications

• Alterations in hepatic perfusion resulting from splanchnic venous luminal compromise caused by pancreatic carcinoma.
• CT angiography: expanded clinical applications.
• CT colonography of colorectal polyps: a metaanalysis.
• CT of the acute abdomen: findings and impact on diagnosis and treatment.
• Cine CT during coughing for assessment of tracheomalacia: preliminary experience with 64-MDCT.
• ECG-gated chest CT angiography with 64-MDCT and tri-phasic IV contrast administration regimen in patients with acute non-specific chest pain.
• Impact of abdominal CT on the management of patients presenting to the emergency department with acute abdominal pain.
• Impact of multidetector CT on donor selection and surgical planning before living adult right lobe liver transplantation.
• Incisional block with bupivacaine for analgesia after celiotomy in dogs.
• Measuring noncalcified coronary atherosclerotic plaque using voxel analysis with MDCT angiography: a pilot clinical study.
• Multidetector CT of potential right-lobe liver donors.
• Multimodality postoperative imaging of liver transplantation.
• Nonopaque crystal deposition causing ureteric obstruction in patients with HIV undergoing indinavir therapy.
• On the value of non-contrast-enhanced CT in blunt abdominal trauma.
• Paddle-wheel CT display of pulmonary arteries and other lung structures: a new imaging approach.
• Pancreatic adenocarcinoma: value of multidetector CT angiography in preoperative evaluation.
• Possible causes of inconclusive results on CT-guided thoracic and abdominal core biopsies.
• Radiofrequency ablation of hepatic tumors: increased tumor destruction with adjuvant liposomal doxorubicin therapy.
• Spiral CT venography of the lower extremity.
• The psychomotor effects of paroxetine alone and in combination with haloperidol, amylobarbitone, oxazepam, or alcohol.
• Ultrasonic pseudocalculus effect in psotcholecystectomy patients.