Two novel C(27)N(3)-type Lycopodium alkaloids, cryptadines A (1) and B (2) consisting of two octahydroquinoline rings (C(11)N) and a piperidine ring (C(5)N), have been isolated from the club moss Lycopodium cryptomerinum, and their structures and relative stereochemistry were elucidated on the basis of spectroscopic data, chemical transformations, and computational methods. Cryptadines A (1) and B (2) exhibited an inhibitory activity against acetylcholinesterase.
Cryptadines A and B, novel C(27)N(3)-type pentacyclic alkaloids from Lycopodium cryptomerinum. Publishing Authors By Initials
Cryptadines A and B, novel C(27)N(3)-type pentacyclic alkaloids from Lycopodium cryptomerinum. Journal Published:
PUBLICATION TYPE: Journal Article
Journal: Bioorganic & medicinal chemistry
VOLUME: 15
Page Numbers: 7803-8
Journal Abbreviation: Bioorg. Med. Chem.
ISSN: 0968-0896
DAY: 28
MONTH: 08
YEAR: 2007
Cryptadines A and B, novel C(27)N(3)-type pentacyclic alkaloids from Lycopodium cryptomerinum. Information
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LANGUAGE: eng
NlmUniqueID: 9413298
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Grant and Affiliation Information for Cryptadines A and B, novel C(27)N(3)-type pentacyclic alkaloids from Lycopodium cryptomerinum.
AFFILIATION: Faculty of Pharmaceutical Sciences, Hoshi University, Ebara 2-4-41 Shinagawa, Tokyo 142-8501, Japan; Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan.
Country: England
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MEDLINETA: Bioorg Med Chem
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