Crossed immunoelectrophoretic analysis of Neisseria meningitidis antigens and of corresponding antibodies in patients with meningococcal disease.

Crossed immunoelectrophoretic analysis of Neisseria meningitidis antigens and of corresponding antibodies in patients with meningococcal disease. Research Abstract Details 

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Crossed immunoelectrophoretic analysis of Neisseria meningitidis antigens and of corresponding antibodies in patients with meningococcal disease. Abstract Text:

Sixty-three different antigens of Neisseria meningitidis groups A, B and C were demonstrated by means of crossed immunoelectrophoresis against rabbit antiserum. The group-specific polysaccharides A and C were identified in the immunoprecipitate pattern. The majority of the remaining antigens were common to all three groups of meningococci. A clearcut rise in antibodies was found in all of 27 patients with meningococcal meningitis or septicaemia. These antibodies were directed against both group-specific antigens and common antigens. No such rise was seen among the 22 patients with purulent meningitis of non-meningococcal etiology. Altogether 15 precipitins were detected in the patients with meningococcal disease. Nine of these antibodies could be identified by comparison with the rabbit antiserum. The antibody rise was semiquantified by means of a scoring system. The rise in the precipitin score of antibodies against common antigens in patients infected with group B meningococci was significantly higher than in patients infected with group A meningococci.

Crossed immunoelectrophoretic analysis of Neisseria meningitidis antigens and of corresponding antibodies in patients with meningococcal disease. Publishing Authors By Initials

For similar bacterial infections and mycoses: infection: sepsis research abstracts see: bacterial infections and mycoses: infection: sepsis research

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MEDLINE DATE:

Crossed immunoelectrophoretic analysis of Neisseria meningitidis antigens and of corresponding antibodies in patients with meningococcal disease. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Acta pathologica et microbiologica Scandinavica. S

VOLUME: 86

Page Numbers: 1-9

Journal Abbreviation:

ISSN: 0304-1328

DAY: 26

MONTH: Feb

YEAR: 1978

Crossed immunoelectrophoretic analysis of Neisseria meningitidis antigens and of corresponding antibodies in patients with meningococcal disease. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 7508469

Crossed immunoelectrophoretic analysis of Neisseria meningitidis antigens and of corresponding antibodies in patients with meningococcal disease. Keywords Mesh Terms:

KEYWORDS: Sepsis

MESH TERMS: immunology

Chemical & Substance for Abstract: Crossed immunoelectrophoretic analysis of Neisseria meningitidis antigens and of corresponding antibodies in patients with meningococcal disease. Information

Substance Name: Immune Sera

Registry Number: 0

Grant and Affiliation Information for Crossed immunoelectrophoretic analysis of Neisseria meningitidis antigens and of corresponding antibodies in patients with meningococcal disease.

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Country: DENMARK

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MEDLINETA: Acta Pathol Microbiol Scand [C

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