Cross-talk between two organs: how the kidney responds to disruption of acid-base balance by the lung.

Cross-talk between two organs: how the kidney responds to disruption of acid-base balance by the lung. Research Abstract Details 

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Cross-talk between two organs: how the kidney responds to disruption of acid-base balance by the lung. Abstract Text:

Hypoventilation increases PaCO(2) (hypercapnia) and initiates the acid-base disorder known as respiratory acidosis. Hyperventilation decreases PaCO(2) (hypocapnia) and initiates the acid-base disorder known as respiratory alkalosis. The impact on acidity of these primary changes in PaCO(2) is ameliorated by secondary, directional changes in plasma bicarbonate concentration that occur in two stages. Acutely, modest changes in plasma bicarbonate originate from titration of the body's nonbicarbonate buffers. In chronic hypercapnia and hypocapnia, larger changes in plasma bicarbonate occur that reflect adjustments in renal acidification mechanisms. As a result, the amelioration of systemic acidity is more pronounced in the chronic forms of the respiratory acid-base disorders.

Cross-talk between two organs: how the kidney responds to disruption of acid-base balance by the lung. Publishing Authors By Initials

For similar respiratory system: lung research abstracts see: respiratory system: lung research

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Cross-talk between two organs: how the kidney responds to disruption of acid-base balance by the lung. Journal Published:

PUBLICATION TYPE: Review

Journal: Nephron. Physiology

VOLUME: 93

Page Numbers: p61-6

Journal Abbreviation: Nephron Physiol

ISSN: 1660-2137

DAY: 8

MONTH: 04

YEAR: 2003

Cross-talk between two organs: how the kidney responds to disruption of acid-base balance by the lung. Information

Number of References: 35

LANGUAGE: eng

NlmUniqueID: 101159772

Cross-talk between two organs: how the kidney responds to disruption of acid-base balance by the lung. Keywords Mesh Terms:

KEYWORDS: Lung

MESH TERMS: physiopathology

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Grant and Affiliation Information for Cross-talk between two organs: how the kidney responds to disruption of acid-base balance by the lung.

AFFILIATION: Department of Medicine, Tufts University School of Medicine, and the Division of Nephrology and the Tupper Research Institute, Tufts-New England Medical Center, Boston, MA 02111, USA. nicolaos.madias@tufts.edu

Country: Switzerland

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MEDLINETA: Nephron Physiol

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