The fractionation of small particles in a liquid based on their size in a micropost array by deterministic lateral displacement was recently demonstrated with unprecedented resolution (L. R. Huang, E. C. Cox, R. H. Austin and J. C. Sturm, Science, 2004, 304, 987-990, ). In this paper, we present a model of how the critical particle size for fractionation depends on the micropost geometry, depending specifically on the gap between posts, the offset of posts in one row with respect to another, and whether the fluid is driven by hydrodynamics or by electroosmosis. In general the critical particle diameter is much smaller than the gap, which prevents clogging. The model is supported by data with particles from 2.3 to 22 microm.
Critical particle size for fractionation by deterministic lateral displacement. Publishing Authors By Initials
Critical particle size for fractionation by deterministic lateral displacement. Journal Published:
PUBLICATION TYPE: Research Support, U.S. Gov't,
Journal: Lab on a chip
VOLUME: 6
Page Numbers: 655-8
Journal Abbreviation:
ISSN: 1473-0197
DAY: 17
MONTH: 03
YEAR: 2006
Critical particle size for fractionation by deterministic lateral displacement. Information
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LANGUAGE: eng
NlmUniqueID: 101128948
Critical particle size for fractionation by deterministic lateral displacement. Keywords Mesh Terms:
KEYWORDS: Silicon Dioxide
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Chemical & Substance for Abstract: Critical particle size for fractionation by deterministic lateral displacement. Information
Substance Name: Graphite
Registry Number: 7782-42-5
Grant and Affiliation Information for Critical particle size for fractionation by deterministic lateral displacement.
AFFILIATION: Princeton Institute for the Science and Technology of Materials, PRISM Princeton University, Princeton, NJ 08544, USA. dinglis@princeton.edu
Country: England
AGENCY: United States NHGRI
GRANT: HG01506
ACRONYM: HG
MEDLINETA: Lab Chip
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