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COX-2 mRNA expression decreases in the subplantar muscle of rat paw subjected to carrageenan-induced inflammation after low level laser therapy.

COX-2 mRNA expression decreases in the subplantar muscle of rat paw subjected to carrageenan-induced inflammation after low level laser therapy. Research Abstract Details 

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  • COX-2 mRNA expression decreases in the subplantar muscle of rat paw subjected to carrageenan-induced inflammation after low level laser therapy. Abstract Text:

    r albertiniR Albertini,f aimbireF Aimbire,a b villaverdeA B Villaverde,j a silvaJ A Silva,m s costaM S Costa,

    OBJECTIVE AND DESIGN: Low level laser therapy (LLLT) has been presented as a novel therapy to treat inflammation. Herein we studied the effect of LLLT on the COX-2 mRNA expression in subplantar tissue taken from rats treated with carrageenan. MATERIAL: The groups consisted of 32 rats: A(1) (Saline), A(2) (Carrageenan), A(3) (Carrageenan + laser 660 nm) and A(4) (Carrageenan + laser 684 nm). TREATMENT: A(3) and A(4) were irradiated in the first hour after carrageenan. METHODS: The edema was measured by a plethysmometer and COX-2 mRNA was by RT-PCR. Statistical were evaluated by ANOVA and Tukey-Kramer Test. RESULTS: Carrageenan increased both edema (A 1)= 0.6 +/- 0.04 vs. A(2)= 2.24 +/- 0.08) and COX-2 mRNA (A(1)= 1.1 +/- 0.26 vs. A(2)= 3.52 +/- 0.69). Irradiation reduced the edema (A(3)= 0.84 +/- 0.09; A(4)= 1.31 +/- 0.05) and the COX-2 mRNA (A(3)= 2.16 +/- 0.28; A(4)= 1.86 +/- 0.20). CONCLUSION: LLLT reduce the expression of COX-2 mRNA.

    COX-2 mRNA expression decreases in the subplantar muscle of rat paw subjected to carrageenan-induced inflammation after low level laser therapy. Publishing Authors By Initials

    r albertiniR Albertini,f aimbireF Aimbire,ab villaverdeAB Villaverde,ja silvaJA Silva,ms costaMS Costa,

    For similar animals: chordata: vertebrates: mammals: rodentia: muridae: murinae: rats: rats, wistar research abstracts see: animals: chordata: vertebrates: mammals: rodentia: muridae: murinae: rats: rats, wistar research

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    COX-2 mRNA expression decreases in the subplantar muscle of rat paw subjected to carrageenan-induced inflammation after low level laser therapy. Journal Published:

    PUBLICATION TYPE: Research Support, Non-U.S. Gov

    Journal: Inflammation research : official journal of the Eu

    VOLUME: 56

    Page Numbers: 228-9

    Journal Abbreviation: Inflamm. Res.

    ISSN: 1023-3830

    DAY: 21

    MONTH: Jun

    YEAR: 2007

    COX-2 mRNA expression decreases in the subplantar muscle of rat paw subjected to carrageenan-induced inflammation after low level laser therapy. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 9508160

    COX-2 mRNA expression decreases in the subplantar muscle of rat paw subjected to carrageenan-induced inflammation after low level laser therapy. Keywords Mesh Terms:

    KEYWORDS: Rats, Wistar

    MESH TERMS: metabolism

    Chemical & Substance for Abstract: COX-2 mRNA expression decreases in the subplantar muscle of rat paw subjected to carrageenan-induced inflammation after low level laser therapy. Information

    Substance Name: Cyclooxygenase 2

    Registry Number: EC 1.14.99.1

    Grant and Affiliation Information for COX-2 mRNA expression decreases in the subplantar muscle of rat paw subjected to carrageenan-induced inflammation after low level laser therapy.

    AFFILIATION: IP&D - UNIVAP, Av, Shishima Hifumi 2911, CEP: 12244-000, São José dos Campos, Brazil.

    Country: Switzerland

    Switzerland Research PublicationSwitzerland Research Publication

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    MEDLINETA: Inflamm Res

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