Course of right and left ventricular function in patients with pulmonary insufficiency after repair of Tetralogy of Fallot.

Course of right and left ventricular function in patients with pulmonary insufficiency after repair of Tetralogy of Fallot. Research Abstract Details 

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Course of right and left ventricular function in patients with pulmonary insufficiency after repair of Tetralogy of Fallot. Abstract Text:

M S Schamberger,R A Hurwitz,

Surgical repair of tetralogy of Fallot (TOF) frequently results in pulmonary valve insufficiency. Nevertheless, no serial information is available on the long-term impact of the valvular insufficiency on right and left ventricular function. Right and left ventricular ejection fraction was measured serially by radionuclide angiocardiography in 21 patients with at least moderate pulmonary insufficiency after repair of TOF. A baseline study was obtained an average of 1.2 years after repair, and a follow-up study was performed an average of 10.2 years after surgery. Changes in ventricular function over time and deviations from the normal range were analyzed. At baseline evaluation the mean right ventricular ejection fraction (RVEF; 0.52 +/- 0.10) and left ventricular ejection fraction (LVEF; 0.68 +/- 0.10) were normal. At the time of follow-up the mean RVEF had significantly decreased to 0.45 +/- 0.09 (p < 0.01). The mean LVEF had decreased to 0.60 +/- 0.11 (p < 0.02). This change was independent of the RVEF (r = -0.13). Eleven patients (52%) had an abnormal RVEF or LVEF at follow-up. Nineteen patients (90%) showed a decrease of 0.05 or more in RVEF, LVEF, or both between studies. These data suggest a negative impact of long-standing pulmonary insufficiency on right and left ventricular systolic function after repair of TOF. Therefore, continued surveillance of biventricular function in this patient population appears warranted.

Course of right and left ventricular function in patients with pulmonary insufficiency after repair of Tetralogy of Fallot. Publishing Authors By Initials

MS Schamberger,RA Hurwitz,

For similar circulatory and respiratory physiology: cardiovascular physiology: cardiovascular physiologic processes: ventricular function: ventricular function, right research abstracts see: circulatory and respiratory physiology: cardiovascular physiology: cardiovascular physiologic processes: ventricular function: ventricular function, right research

PUBMED ID PMID:

MEDLINE DATE: 2000 May-Jun

Course of right and left ventricular function in patients with pulmonary insufficiency after repair of Tetralogy of Fallot. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Pediatric cardiology

VOLUME: 21

Page Numbers: 244-8

Journal Abbreviation: Pediatr Cardiol

ISSN: 0172-0643

DAY: 20

MONTH: 02

YEAR: 2008

Course of right and left ventricular function in patients with pulmonary insufficiency after repair of Tetralogy of Fallot. Information

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LANGUAGE: eng

NlmUniqueID: 8003849

Course of right and left ventricular function in patients with pulmonary insufficiency after repair of Tetralogy of Fallot. Keywords Mesh Terms:

KEYWORDS: Ventricular Function, Right

MESH TERMS: surgery

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Grant and Affiliation Information for Course of right and left ventricular function in patients with pulmonary insufficiency after repair of Tetralogy of Fallot.

AFFILIATION: Department of Pediatrics, Section of Pediatric Cardiology, James Whitcomb Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, IN 46202-5225, USA.

Country: UNITED STATES

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MEDLINETA: Pediatr Cardiol

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