Course of depressive symptoms and medication adherence after acute coronary syndromes: an electronic medication monitoring study.

Course of depressive symptoms and medication adherence after acute coronary syndromes: an electronic medication monitoring study. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Course of depressive symptoms and medication adherence after acute coronary syndromes: an electronic medication monitoring study. Abstract Text:

OBJECTIVES: We tested whether improvements in depressive symptoms precede improved adherence to aspirin in patients with acute coronary syndromes (ACS). BACKGROUND: Depression is associated with medication nonadherence in patients with ACS, but it is unclear whether changes in depression impact on adherence. METHODS: Electronic medication monitoring was used to measure adherence to aspirin during a 3-month period in a consecutive cohort of 172 patients (25 to 85 years) recruited within 1 week of hospitalization for ACS. Depressive symptom severity was assessed using the Beck Depression Inventory (BDI) during hospitalization and at 1 and 3 months after hospitalization. Adherence was defined as the percentage of days aspirin was taken as prescribed. RESULTS: Depression severity in hospital was associated with nonadherence in a gradient fashion: 15% of non-depressed patients (BDI score 0 to 4), 29% of mildly depressed patients (BDI score 10 to 16), and 37% of patients with moderately-to-severely depressive symptoms (BDI score >16) took aspirin less than 80% of the time (p = 0.03). A cross-lagged path analytic model revealed that improvements in depressive symptoms in the first month after the ACS were associated with improvements in adherence rates in the subsequent 2 months (standardized direct effect -0.32, p = 0.016). CONCLUSIONS: Diagnosis and treatment of depressive symptoms may improve medication adherence in patients after ACS.

Course of depressive symptoms and medication adherence after acute coronary syndromes: an electronic medication monitoring study. Publishing Authors By Initials

For similar natural sciences: time: time factors research abstracts see: natural sciences: time: time factors research

PUBMED ID PMID:

MEDLINE DATE:

Course of depressive symptoms and medication adherence after acute coronary syndromes: an electronic medication monitoring study. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: Journal of the American College of Cardiology

VOLUME: 48

Page Numbers: 2218-22

Journal Abbreviation: J. Am. Coll. Cardiol.

ISSN: 1558-3597

DAY: 13

MONTH: 11

YEAR: 2006

Course of depressive symptoms and medication adherence after acute coronary syndromes: an electronic medication monitoring study. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 8301365

Course of depressive symptoms and medication adherence after acute coronary syndromes: an electronic medication monitoring study. Keywords Mesh Terms:

KEYWORDS: Time Factors

MESH TERMS: psychology

Chemical & Substance for Abstract: Course of depressive symptoms and medication adherence after acute coronary syndromes: an electronic medication monitoring study. Information

Substance Name: Aspirin

Registry Number: 50-78-2

Grant and Affiliation Information for Course of depressive symptoms and medication adherence after acute coronary syndromes: an electronic medication monitoring study.

AFFILIATION: Department of Psychiatry, Mount Sinai School of Medicine, New York, New York, USA.

Country: United States

AGENCY: United States NHLBI

GRANT: HL-076857

ACRONYM: HL

MEDLINETA: J Am Coll Cardiol

REFSOURCE: J Am Coll Cardiol. 2006 Dec 5;48(11):222

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Course of depressive symptoms and medication adherence after acute coronary syndromes: an electronic medication monitoring study Related Publications

• (Pro)Insulin processing: a historical perspective.
• Adjuvant hormonal therapy for premenopausal women with breast cancer.
• Amygdala volume and nonverbal social impairment in adolescent and adult males with autism.
• Ceramide structural features required to stimulate ABCA1-mediated cholesterol efflux to apolipoprotein A-I.
• Comparing tongue shapes from ultrasound imaging using smoothing spline analysis of variance.
• Consistent relationships between sensory properties of savory snack foods and calories influence food intake in rats.
• Course of depressive symptoms and medication adherence after acute coronary syndromes: an electronic medication monitoring study.
• Depression vulnerabilities in patients with different levels of depressive symptoms after acute coronary syndromes.
• Difference spectrophotometric assay of 1,2-diphenolic drugs in pharmaceutical formulations - I. Boric acid reagent.
• Difference spectrophotometric assay of 1,2-diphenolic drugs in pharmaceutical formulations -III. The simultaneous assay of levodopa and benserazide.
• Effects of stimulus level on the speech perception abilities of children using cochlear implants or digital hearing AIDS.
• Event-related functional magnetic resonance imaging measures of neural activity to positive social stimuli in pre- and post-treatment depression.
• Granular cell tumour of the bile duct mimicking distal cholangiocarcinoma: one case report and review of the literature.
• High regulatory gene use in sea urchin embryogenesis: Implications for bilaterian development and evolution.
• Hindgut specification and cell-adhesion functions of Sphox11/13b in the endoderm of the sea urchin embryo.
• Identification and characterization of homeobox transcription factor genes in Strongylocentrotus purpuratus, and their expression in embryonic development.
• Kava in generalized anxiety disorder: three placebo-controlled trials.
• Mechanistic possibilities in MauG-dependent tryptophan tryptophylquinone biosynthesis.
• POLARIZED ABSORPTION SPECTRA OF SINGLE CRYSTALS OF 1-METHYLTHYMINE, 9-METHYLADENINE, AND THEIR HYDROGEN-BONDED COMPLEX.
• Peripartum changes in the bovine placenta related to fetal membrane retention.
• Persistent depression affects adherence to secondary prevention behaviors after acute coronary syndromes.
• Persistent depressive symptoms lower aspirin adherence after acute coronary syndromes.
• Pharmacist staffing, technology use, and implementation of medication safety practices in rural hospitals.
• Premorbid intra-individual variability in intellectual performance and risk for schizophrenia: a population-based study.
• Protection against Western diet-induced obesity and hepatic steatosis in liver fatty acid-binding protein knockout mice.
• RNA polymerase III transcribes human microRNAs.
• Silencing estrogen receptor alpha in breast cancer cells.
• The C2H2 zinc finger genes of Strongylocentrotus purpuratus and their expression in embryonic development.
• The temperature dependence of derivative ultraviolet absorption spectra.
• What else can we do to combat stigma?