Cotton wool spots associated with interferon beta-1 alpha therapy.

Cotton wool spots associated with interferon beta-1 alpha therapy. Research Abstract Details 

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Cotton wool spots associated with interferon beta-1 alpha therapy. Abstract Text:

PURPOSE: To describe a case of cotton wool spots associated with interferon beta-1a treatment. METHODS: Observational case report. RESULTS: A 40-year-old man with a history of multiple sclerosis was on interferon beta-1a. He presented with cotton wool spots on fundus exam, which resolved and then recurred all while on therapy. Interferon was discontinued after the second episode and again the cotton wool spots resolved. Upon restarting the interferon, no further cotton wool spots have recurred. CONCLUSION: To our knowledge this represents only the third case of interferon beta-1a associated cotton wool patches and the first in the English-language ophthalmic literature. Unlike interferon alpha therapy, interferon beta 1-a retinopathy is presumed to be extremely rare and more common etiologies for cotton wool spots should be excluded in these patients. Given this limited number of cases versus the relatively frequent use of interferon beta-1a in the management of multiple sclerosis, no conclusions regarding causality or screening can be made but the issue probably deserves further study.

Cotton wool spots associated with interferon beta-1 alpha therapy. Publishing Authors By Initials

For similar eye diseases: retinal diseases research abstracts see: eye diseases: retinal diseases research

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Cotton wool spots associated with interferon beta-1 alpha therapy. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Seminars in ophthalmology

VOLUME: 22

Page Numbers: 49-53

Journal Abbreviation: Semin Ophthalmol

ISSN: 0882-0538

DAY: 28

MONTH: 05

YEAR: 2008

Cotton wool spots associated with interferon beta-1 alpha therapy. Information

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LANGUAGE: eng

NlmUniqueID: 8610759

Cotton wool spots associated with interferon beta-1 alpha therapy. Keywords Mesh Terms:

KEYWORDS: Retinal Diseases

MESH TERMS: pathology

Chemical & Substance for Abstract: Cotton wool spots associated with interferon beta-1 alpha therapy. Information

Substance Name: Interferon-beta

Registry Number: 77238-31-4

Grant and Affiliation Information for Cotton wool spots associated with interferon beta-1 alpha therapy.

AFFILIATION: University of Iowa Hospitals and Clinics, Iowa City, IA 52242, USA.

Country: United States

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MEDLINETA: Semin Ophthalmol

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