Cost-effectiveness analysis in diagnosis of coronary artery disease: choice of laboratory markers.

Cost-effectiveness analysis in diagnosis of coronary artery disease: choice of laboratory markers. Research Abstract Details 

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Cost-effectiveness analysis in diagnosis of coronary artery disease: choice of laboratory markers. Abstract Text:

Natasa Bogavac-Stanojevi?,Guenka Ivanova Petrova,Zorana Jeli?-Ivanovi?,Lidija Memon,Slavica Spasi?,Natasa Bogavac-Stanojevi?,Guenka Ivanova Petrova,Zorana Jeli?-Ivanovi?,Lidija Memon,Slavica Spasi?,

OBJECTIVES: The aim of our study was to determine the cost-effectiveness of coronary artery disease (CAD) diagnostic parameters in a clinical laboratory setting. DESIGN AND METHODS: The effectiveness of apolipoproteins, lipoproteins and high sensitivity C-reactive protein (hs-CRP) supplementary to Framingham scoring data within a CAD risk assessment procedure was established in 221 CAD patients and 289 controls. The total costs of diagnostic procedures were calculated and incremental cost-effectiveness analysis was applied. RESULTS: A diagnostic strategy employing Framingham calculation followed by apolipoprotein A-I (apoA-I) had the lowest cost per additional successfully diagnosed patient than the same strategy followed by hs-CRP in the low (2.63 vs. 24.47 euros) and intermediate-risk groups (2.96 vs. 122.85 euros). In the high-risk group the diagnostic strategy employing apoA-I saved 9.14 euros in comparison to the strategy employing hs-CRP. CONCLUSION: Cost-effectiveness analysis of different diagnostic markers results in improved identification of at-risk patients at a lower health cost for society.

Cost-effectiveness analysis in diagnosis of coronary artery disease: choice of laboratory markers. Publishing Authors By Initials

N Bogavac-Stanojevi?,G Ivanova Petrova,Z Jeli?-Ivanovi?,L Memon,S Spasi?,N Bogavac-Stanojevi?,G Ivanova Petrova,Z Jeli?-Ivanovi?,L Memon,S Spasi?,

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Cost-effectiveness analysis in diagnosis of coronary artery disease: choice of laboratory markers. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Clinical biochemistry

VOLUME: 40

Page Numbers: 1180-7

Journal Abbreviation: Clin. Biochem.

ISSN: 0009-9120

DAY: 10

MONTH: 08

YEAR: 2007

Cost-effectiveness analysis in diagnosis of coronary artery disease: choice of laboratory markers. Information

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LANGUAGE: eng

NlmUniqueID: 133660

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AFFILIATION: Institute of Medical Biochemistry, Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia. naca@pharmacy.bg.ac.yu

Country: United States

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MEDLINETA: Clin Biochem

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