Corticosteroids and chronic lung disease in extremely immature infants: a dilemma.

Corticosteroids and chronic lung disease in extremely immature infants: a dilemma. Research Abstract Details 

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Corticosteroids and chronic lung disease in extremely immature infants: a dilemma. Abstract Text:

What is the balance of benefits and risks of dexamethasone in extremely immature infants? The answer remains unclear. We feel that the risks of "early" treatment outweigh the benefits, because many infants who would not develop CLD will be treated. Treatment between day 7 and day 14 seems more appropriate to us, as it focuses on infants with a high risk of developing CLD. However, the lungs may be already somewhat damaged when starting treatment, whose expected benefit is a shortened duration of mechanical ventilation and a decreased incidence of CLD. The risks for growth and brain development are not clearly assessed. Both 7-day courses and pulse therapy are effective, but no comparison of these 2 schedules has been published. We therefore do not know whether pulse therapy provides the same benefits as 7-day courses with fewer risks for growth or cardiomyopathy.

Corticosteroids and chronic lung disease in extremely immature infants: a dilemma. Publishing Authors By Initials

For similar respiratory tract diseases: lung diseases research abstracts see: respiratory tract diseases: lung diseases research

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Corticosteroids and chronic lung disease in extremely immature infants: a dilemma. Journal Published:

PUBLICATION TYPE: Review

Journal: Pediatric pulmonology. Supplement

VOLUME: 18

Page Numbers: 209-11

Journal Abbreviation:

ISSN: 1054-187X

DAY: 26

MONTH: 02

YEAR: 1999

Corticosteroids and chronic lung disease in extremely immature infants: a dilemma. Information

Number of References: 12

LANGUAGE: eng

NlmUniqueID: 9014095

Corticosteroids and chronic lung disease in extremely immature infants: a dilemma. Keywords Mesh Terms:

KEYWORDS: Lung Diseases

MESH TERMS: drug therapy

Chemical & Substance for Abstract: Corticosteroids and chronic lung disease in extremely immature infants: a dilemma. Information

Substance Name: Dexamethasone

Registry Number: 50-02-2

Grant and Affiliation Information for Corticosteroids and chronic lung disease in extremely immature infants: a dilemma.

AFFILIATION: Service de Médecine Néconatale de Port-Royal, UFR Cochin Port-Royal, Université René Descartes, Paris, France.

Country: UNITED STATES

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MEDLINETA: Pediatr Pulmonol Suppl

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