Cortical activation mapping of epileptiform activity derived from interictal ECoG spikes.

Cortical activation mapping of epileptiform activity derived from interictal ECoG spikes. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Cortical activation mapping of epileptiform activity derived from interictal ECoG spikes. Abstract Text:

Yuan Lai,Wim van Drongelen,Kurt Hecox,David Frim,Michael Kohrman,Bin He,

PURPOSE: To develop and evaluate a new cortical activation mapping (CAM) method to obtain the neuronal activation sequences from the cortical potential distributions. METHODS: Interictal electrocorticogram (ECoG) recordings were analyzed for eight pediatric epilepsy patients to find the cortical activation maps, which were compared with the patients' seizure-onset zones identified from ictal ECoG recordings. Various relations between the local activation time and cortical potential were assumed. The most effective relation was determined by accessing their capability to predict the seizure-onset zone. Computer simulations using a moving dipole source model were also conducted to test the present approach in imaging the propagated cortical activity. RESULTS: In both clinical data analysis and computer simulations, the maximal amplitude proved to be the most effective criterion with which to determine the local cortical activation time. The present method successfully predicted the seizure-onset zone in seven of eight patients by the CAM analysis of ECoG-recorded interictal spikes (IISs). For patients with multiple seizure foci, each focus can be revealed by analyzing IISs with different spatial patterns. CONCLUSIONS: The time difference between spike peaks of the interictal events in the leading channel and other channels can be effectively defined as the local cortical activation time. The cortical activation mapping method based on this time latency can be used to predict the seizure-onset zones, suggesting that the present CAM method is useful to assist the presurgical evaluation for the epilepsy patients.

Cortical activation mapping of epileptiform activity derived from interictal ECoG spikes. Publishing Authors By Initials

Y Lai,W van Drongelen,K Hecox,D Frim,M Kohrman,B He,

For similar diagnosis: prognosis research abstracts see: diagnosis: prognosis research

PUBMED ID PMID:

MEDLINE DATE:

Cortical activation mapping of epileptiform activity derived from interictal ECoG spikes. Journal Published:

PUBLICATION TYPE: Research Support, U.S. Gov't,

Journal: Epilepsia

VOLUME: 48

Page Numbers: 305-14

Journal Abbreviation: Epilepsia

ISSN: 0013-9580

DAY: 3

MONTH: Feb

YEAR: 2007

Cortical activation mapping of epileptiform activity derived from interictal ECoG spikes. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 2983306

Cortical activation mapping of epileptiform activity derived from interictal ECoG spikes. Keywords Mesh Terms:

KEYWORDS: Prognosis

MESH TERMS: physiopathology

Chemical & Substance for Abstract: Cortical activation mapping of epileptiform activity derived from interictal ECoG spikes. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Cortical activation mapping of epileptiform activity derived from interictal ECoG spikes.

AFFILIATION: Department of Biomedical Engineering, University of Minnesota, Minneapolis, Minnesota 55455, USA.

Country: United States

AGENCY: United States NIBIB

GRANT: R01 EB00178

ACRONYM: EB

MEDLINETA: Epilepsia

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Cortical activation mapping of epileptiform activity derived from interictal ECoG spikes Related Publications

• Action of genistein on tension of isolated rabbit femoral artery and its mechanism.
• Characterization of the distinct orthotopic bone-forming activity of 14 BMPs using recombinant adenovirus-mediated gene delivery.
• Effect of agmatine on intracellular free calcium concentration in isolated rat ventricular myocytes.
• Effects of pregnancy cocaine exposure on the mother and fetus: a murine model.
• Inhibitor of DNA binding/differentiation helix-loop-helix proteins mediate bone morphogenetic protein-induced osteoblast differentiation of mesenchymal stem cells.
• Isolation, culture and identification of human venous malformation endothelial cells.
• Microinjection of adrenomedullin into rostral ventrolateral medulla increases blood pressure, heart rate and renal sympathetic nerve activity in rats.
• Responses of regional vascular beds to local injection of genistein in rats.
• [A case of nt 1004C --> A G6PD gene mutation in Yunnan Han people]
• [A serial study of in cytogenetic change and morphology on the tetra-arsenic tetra-sulfide treatment in untreated or recurrent acute promyelocytic leukemia]
• [An experimental study on the prevention and treatment of postburn intestinal injury and bacterial translocation by Sijunzi decoction in scalded rats]
• [Diagnosis and treatment of primary hyperparathyroidism]
• [Effect of a proteinase-activated receptor-2 (PAR-2) agonist on tryptase release from human mast cells]
• [Effect of curcumin on STAT5 signaling molecule in K562 cells]
• [Eosinophil specific active markers in allergy]
• [Expressions of peripheral lymph node addressin and GlcNAc-6-sulfotransferase in endometrium and their impacts on implantation.]
• [Generation of human monoclonal antibodies against hemorrhagic fever with renal sydrome (HFRS) virus]
• [Investigation of nuclear Ca2+ regulation in the isolated cardiac nuclei]
• [Mechanism of the role of electrical field in electrical injury]
• [Modulatory effects of capsaicin-sensitive nerve fiber on cardiovascular activity]
• [Phytoestrogen genistein inhibits carotid sinus baroreflex in anesthetized male rats]
• [Preparation and characterization of a McAb against tissue factor pathway inhibitor]
• [Pulmonary alveolar proteinosis: a report of 2 cases, with literature review]
• [Stimulation single fiber electromyography in rats with myasthenia induced by organophosphorus insecticides and their mixtures poisoning]
• [Study of correlation dimension on EEG]
• [The effect of V-shaped Niti alloy implantation on acetabular dysplasia: an experimental study]
• [The polymorphism of delta-aminolevulinic acid dehydratase and genetic susceptibility to lead toxicity in Uighur and Yi population in China]
• [The relationship between nm23-H1 loss of heterozygosity and metastasis in hepatocellular carcinoma]
• [Transmission disequilibrium test of polymorphisms of serotonin transporter gene and schizophrenia based on family trios]
• [Treatment of nodular vasculitis based on syndrome differentiation: a report of 32 cases]