Correlating MRI and histologic tumor thickness in the assessment of oral tongue cancer.

Correlating MRI and histologic tumor thickness in the assessment of oral tongue cancer. Research Abstract Details 

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Correlating MRI and histologic tumor thickness in the assessment of oral tongue cancer. Abstract Text:

Paul Lam,Kai Ming Au-Yeung,Pui Wai Cheng,William Ignace Wei,Anthony Po-Wing Yuen,Nigel Trendell-Smith,Jimmy H C Li,Raymond Li,

OBJECTIVE: Tumor thickness in oral tongue cancer is an important independent prognostic factor for local recurrence, nodal metastasis, and patient survival. An accurate preoperative assessment of tumor thickness is therefore essential for optimal treatment planning. The aim of our study was to evaluate the accuracy of MRI findings for the preoperative measurement of tumor thickness. SUBJECTS AND METHODS. Eighteen patients with oral tongue cancer underwent preoperative MRI of the tongue. After surgery, the glossectomy specimens were serially sectioned. The radiologic tumor thickness of contrast-enhanced T1-weighted and T2-weighted images was compared with the histologic tumor thickness using our proposed tumor thickness staging classifications. These included stage I (tumor < or = 3 mm), stage II (> 3 mm but < or = 9 mm) and stage III (> 9 mm). RESULTS: The overall accuracy in assessment of proposed tumor thickness staging using contrast-enhanced T1-weighted and T2-weighted images was 83% and 56%, respectively. The radiologic tumor thickness as measured on contrast-enhanced T1-weighted and T2-weighted images had significant correlation with histologic tumor thickness (R = 0.938 and 0.941, respectively). CONCLUSION: MR images provide satisfactory accuracy for the measurement of tumor thickness and staging of oral tongue cancer. Preoperative MRI is recommended to assist in treatment planning for patients with this disease.

Correlating MRI and histologic tumor thickness in the assessment of oral tongue cancer. Publishing Authors By Initials

P Lam,KM Au-Yeung,PW Cheng,WI Wei,AP Yuen,N Trendell-Smith,JH Li,R Li,

For similar neoplasms: neoplasms by site: head and neck neoplasms: mouth neoplasms: tongue neoplasms research abstracts see: neoplasms: neoplasms by site: head and neck neoplasms: mouth neoplasms: tongue neoplasms research

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Correlating MRI and histologic tumor thickness in the assessment of oral tongue cancer. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: AJR. American journal of roentgenology

VOLUME: 182

Page Numbers: 803-8

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ISSN: 0361-803X

DAY: 15

MONTH: Mar

YEAR: 2004

Correlating MRI and histologic tumor thickness in the assessment of oral tongue cancer. Information

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LANGUAGE: eng

NlmUniqueID: 7708173

Correlating MRI and histologic tumor thickness in the assessment of oral tongue cancer. Keywords Mesh Terms:

KEYWORDS: Tongue Neoplasms

MESH TERMS: surgery

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Grant and Affiliation Information for Correlating MRI and histologic tumor thickness in the assessment of oral tongue cancer.

AFFILIATION: Division of Otorhinolaryngology, Head and Neck Surgery, Department of Surgery, The University of Hong Kong Medical Centre, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong ROC.

Country: United States

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MEDLINETA: AJR Am J Roentgenol

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