Corneal thickness and endothelial density before and after cataract surgery.

Corneal thickness and endothelial density before and after cataract surgery. Research Abstract Details 

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Corneal thickness and endothelial density before and after cataract surgery. Abstract Text:

BACKGROUND/AIMS: Deturgescence of the corneal stroma is controlled by the pumping action of the endothelial layer and can be monitored by measurement of central corneal thickness (pachymetry). Loss or damage of endothelial cells leads to an increase in corneal thickness, which may ultimately induce corneal decompensation and loss of vision. Little is known about the effect of moderate reductions in endothelial cell number on the thickness of the corneal stroma. This study aimed to investigate this matter further using patients who had incurred moderate decreases in their endothelial cell counts as a result of cataract surgery. METHODS: Central corneal thickness was measured 1 day before surgery, 1 day after surgery, and again at 3 months or 1 year. Endothelial cell counts were also performed 1 day before surgery and thereafter at 3 months or 1 year after surgery. The relationship between these two parameters was assessed statistically. Precise measurements of central corneal thickness were made by optical low coherence reflectometry. For comparative purposes, this parameter was also determined by ultrasonic pachymetry. Central corneal endothelial cell numerical density was estimated on photomicrographs taken with a specular microscope. RESULTS: All patients had significant postoperative corneal swelling on the day after surgery; preoperative values were restored by 3 and 12 months, even though significant endothelial cell losses had occurred. No correlation existed between central corneal thickness and central corneal endothelial cell numerical density. Measurements estimated by ultrasonic pachymetry were more variable and significantly higher than those determined by optical low coherence reflectometry. CONCLUSION: As long as the numerical density of the corneal endothelial cells does not fall below the physiological threshold, a moderate decrease in this parameter does not compromise the pumping activity of the layer as a whole.

Corneal thickness and endothelial density before and after cataract surgery. Publishing Authors By Initials

For similar surgical procedures, operative: postoperative period research abstracts see: surgical procedures, operative: postoperative period research

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Corneal thickness and endothelial density before and after cataract surgery. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: The British journal of ophthalmology

VOLUME: 85

Page Numbers: 18-20

Journal Abbreviation: Br J Ophthalmol

ISSN: 0007-1161

DAY: 28

MONTH: Jan

YEAR: 2001

Corneal thickness and endothelial density before and after cataract surgery. Information

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LANGUAGE: eng

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Corneal thickness and endothelial density before and after cataract surgery. Keywords Mesh Terms:

KEYWORDS: Postoperative Period

MESH TERMS: pathology

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Grant and Affiliation Information for Corneal thickness and endothelial density before and after cataract surgery.

AFFILIATION: Augenklinik des Inselspitals, Universität Bern, CH-3010 Bern, Switzerland.

Country: ENGLAND

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MEDLINETA: Br J Ophthalmol

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