Copper(II)-quenched oligonucleotide probes for fluorescent DNA sensing.

Copper(II)-quenched oligonucleotide probes for fluorescent DNA sensing. Research Abstract Details 

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Copper(II)-quenched oligonucleotide probes for fluorescent DNA sensing. Abstract Text:

Jens Brunner,Roland Kraemer,

A copper(II)-quenched molecular beacon was prepared by attaching fluorescein to the 3'-end and a copper(II) complex to the 5'-end of DNA. In the presence of complementary DNA, copper(II) and dye are spatially separated in the duplex and fluorescence increases up to 15-fold, with excellent discrimination of single base mismatches.

Copper(II)-quenched oligonucleotide probes for fluorescent DNA sensing. Publishing Authors By Initials

J Brunner,R Kraemer,

For similar investigative techniques: chemistry, analytical: photometry: luminescent measurements: fluorometry: spectrometry, fluorescence research abstracts see: investigative techniques: chemistry, analytical: photometry: luminescent measurements: fluorometry: spectrometry, fluorescence research

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Copper(II)-quenched oligonucleotide probes for fluorescent DNA sensing. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Journal of the American Chemical Society

VOLUME: 126

Page Numbers: 13626-7

Journal Abbreviation: J. Am. Chem. Soc.

ISSN: 0002-7863

DAY: 27

MONTH: Oct

YEAR: 2004

Copper(II)-quenched oligonucleotide probes for fluorescent DNA sensing. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 7503056

Copper(II)-quenched oligonucleotide probes for fluorescent DNA sensing. Keywords Mesh Terms:

KEYWORDS: Spectrometry, Fluorescence

MESH TERMS: chemistry

Chemical & Substance for Abstract: Copper(II)-quenched oligonucleotide probes for fluorescent DNA sensing. Information

Substance Name: DNA

Registry Number: 9007-49-2

Grant and Affiliation Information for Copper(II)-quenched oligonucleotide probes for fluorescent DNA sensing.

AFFILIATION: Anorganisch-Chemisches Institut, Universität Heidelberg, Im Neuenheimer Feld 270, 69120 Heidelberg, Germany.

Country: United States

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MEDLINETA: J Am Chem Soc

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