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Controlling Hair Follicle Signaling Pathways through Polyubiquitination.

Controlling Hair Follicle Signaling Pathways through Polyubiquitination. Research Abstract Details 

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  • Controlling Hair Follicle Signaling Pathways through Polyubiquitination. Abstract Text:

    Hair follicle development and maintenance require precise reciprocal signaling interactions between the epithelium and underlying dermis. Three major developmental signaling pathways, Wnt, Sonic hedgehog, and NF-kappaB/Edar, are indispensable for this process and, when aberrantly activated, can lead to skin and appendage neoplasms. Recent data point to protein polyubiquitination as playing a central role in regulating the timing, duration, and location of signaling. Here we review how polyubiquitination regulates the stability and interaction of key signaling components that control hair follicle development and regeneration.Journal of Investigative Dermatology (2008) 128, 1081-1087; doi:10.1038/sj.jid.5700957.

    Controlling Hair Follicle Signaling Pathways through Polyubiquitination. Publishing Authors By Initials

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    PUBMED ID PMID:

    MEDLINE DATE:

    Controlling Hair Follicle Signaling Pathways through Polyubiquitination. Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: The Journal of investigative dermatology

    VOLUME: 128

    Page Numbers: 1081-7

    Journal Abbreviation: J. Invest. Dermatol.

    ISSN: 1523-1747

    DAY: 14

    MONTH: May

    YEAR: 2008

    Controlling Hair Follicle Signaling Pathways through Polyubiquitination. Information

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    LANGUAGE: eng

    NlmUniqueID: 426720

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    Grant and Affiliation Information for Controlling Hair Follicle Signaling Pathways through Polyubiquitination.

    AFFILIATION: 1Program in Epithelial Biology, Stanford University, Stanford, California, USA.

    Country: United States

    United States Research PublicationUnited States Research Publication

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    MEDLINETA: J Invest Dermatol

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