Controlled inspiration depth reduces variance in breath-holding-induced BOLD signal.

Controlled inspiration depth reduces variance in breath-holding-induced BOLD signal. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Controlled inspiration depth reduces variance in breath-holding-induced BOLD signal. Abstract Text:

Moriah E Thomason,Gary H Glover,Moriah E Thomason,Gary H Glover,Moriah E Thomason,Gary H Glover,

Recent studies have shown that blood oxygen level dependent (BOLD) response amplitude during short periods of breath holding (BH) measured by functional magnetic resonance imaging (fMRI) can be an effective metric for intersubject calibration procedures. However, inconsistency in the depth of inspiration during the BH scan may account for a portion of BOLD variation observed in such scans, and it is likely to reduce the effectiveness of the calibration measurement. While modulation of BOLD signal has been correlated with end-tidal CO(2) and other measures of breathing, fluctuations in performance of BH have not been studied in the context of their impact on BOLD signal. Here, we studied the degree to which inspiration depth corresponds to BOLD signal change and tested the effectiveness of a method designed to control inspiration level through visual cues during the BH task paradigm. We observed reliable differences in BOLD signal amplitude corresponding to the depth of inspiration. It was determined that variance in BOLD signal response to BH could be significantly reduced when subjects were given visual feedback during task inspiration periods. The implications of these findings for routine BH studies of BOLD-derived neurovascular response are discussed.

Controlled inspiration depth reduces variance in breath-holding-induced BOLD signal. Publishing Authors By Initials

ME Thomason,GH Glover,ME Thomason,GH Glover,ME Thomason,GH Glover,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Controlled inspiration depth reduces variance in breath-holding-induced BOLD signal. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: NeuroImage

VOLUME: 39

Page Numbers: 206-14

Journal Abbreviation: Neuroimage

ISSN: 1053-8119

DAY: 24

MONTH: 08

YEAR: 2007

Controlled inspiration depth reduces variance in breath-holding-induced BOLD signal. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 9215515

Controlled inspiration depth reduces variance in breath-holding-induced BOLD signal. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Controlled inspiration depth reduces variance in breath-holding-induced BOLD signal. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Controlled inspiration depth reduces variance in breath-holding-induced BOLD signal.

AFFILIATION: Stanford University School of Medicine, Neurosciences Program, Stanford, CA 94305, USA.

Country: United States

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Neuroimage

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Controlled inspiration depth reduces variance in breath-holding-induced BOLD signal Related Publications

• A novel VEGFR3 mutation causes Milroy disease.
• A technique for pulmonary segmental delineation.
• Amniotic fluid testosterone: relationship with cortisol and gestational age.
• Antenatal maternal stress and long-term effects on child neurodevelopment: how and why?
• Assessing the influence of scanner background noise on auditory processing. I. An fMRI study comparing three experimental designs with varying degrees of scanner noise.
• Assessing the influence of scanner background noise on auditory processing. II. An fMRI study comparing auditory processing in the absence and presence of recorded scanner noise using a sparse design.
• Changing cultures: enhancing mental health and wellbeing of refugee young people through education and training.
• Chemistry of 4-alkylaryloxenium ion "precursors": sound and fury signifying something?
• Chromosome fragile sites.
• Controlled inspiration depth reduces variance in breath-holding-induced BOLD signal.
• DSAS-6 organizes a tube-like centriole precursor, and its absence suggests modularity in centriole assembly.
• Effect of the hypocholesterolemic drug, AY 9944, on the absorption of retinol in the rat.
• Endogenous oxidized indoles share inhibitory potency against [3H]isatin binding in rat brain.
• Frontostriatal connectivity and its role in cognitive control in parent-child dyads with ADHD.
• Macular degeneration: types, causes, and possible interventions.
• Management of allergic sinusitis.
• Maternal stress during pregnancy predicts cognitive ability and fearfulness in infancy.
• Parental and adolescent smoking: does the association vary with gender and ethnicity?
• Poultry disease problems in Ontario.
• ROCK-II mediates colon cancer invasion via regulation of MMP-2 and MMP-13 at the site of invadopodia as revealed by multiphoton imaging.
• Reducing interscanner variability of activation in a multicenter fMRI study: controlling for signal-to-fluctuation-noise-ratio (SFNR) differences.
• Relationship between hypoxia, oxygen consumption and body temperature.
• Restricted field of view magnetic resonance imaging of a dynamic time series.
• Spatiotemporal patterns of neurogenesis in the appendicularian Oikopleura dioica.
• State mental health policy: critical priorities confronting state mental health agencies.
• The clinical and economic potential of hyperbaric oxygen therapy in the treatment of diabetic ulceration and other conditions.
• The personal librarian program:an evaluation of a cushing/whitney medical library outreach initiative.
• The role of steric effects in the direct mutagenicity of N-acyloxy-N-alkoxyamides.
• Three-dimensional spiral technique for high-resolution functional MRI.
• [Not Available.]