Contribution of intermediate progenitor cells to cortical histogenesis.

Contribution of intermediate progenitor cells to cortical histogenesis. Research Abstract Details 

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Contribution of intermediate progenitor cells to cortical histogenesis. Abstract Text:

Stephen C Noctor, ,Arnold R Kriegstein,

The mammalian cerebral cortex is the most cellularly complex structure in the animal kingdom. Almost all cortical neurons are produced during a limited embryonic period by cortical progenitor cells in a proliferative region that surrounds the ventricular system of the developing brain. The proliferative region comprises 2 distinct zones, the ventricular zone, which is a neuroepithelial layer directly adjacent to the ventricular lumen, and the subventricular zone, which is positioned superficial to the ventricular zone. Recent advances in molecular and cell biology have made possible the study of specific cell populations, and 2 cortical progenitor cell types, radial glial cells in the ventricular zone and intermediate progenitor cells in the subventricular zone, have been shown to generate neurons in the embryonic cerebral cortex. These findings have refined our understanding of cortical neurogenesis, with implications for understanding the causes of neurodevelopmental disorders and for their potential treatment.

Contribution of intermediate progenitor cells to cortical histogenesis. Publishing Authors By Initials

SC Noctor,V ,AR Kriegstein,

For similar cells: stem cells research abstracts see: cells: stem cells research

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Contribution of intermediate progenitor cells to cortical histogenesis. Journal Published:

PUBLICATION TYPE: Review

Journal: Archives of neurology

VOLUME: 64

Page Numbers: 639-42

Journal Abbreviation: Arch. Neurol.

ISSN: 0003-9942

DAY: 3

MONTH: May

YEAR: 2007

Contribution of intermediate progenitor cells to cortical histogenesis. Information

Number of References: 12

LANGUAGE: eng

NlmUniqueID: 372436

Contribution of intermediate progenitor cells to cortical histogenesis. Keywords Mesh Terms:

KEYWORDS: Stem Cells

MESH TERMS: physiology

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Grant and Affiliation Information for Contribution of intermediate progenitor cells to cortical histogenesis.

AFFILIATION: Department of Neurology, Institute for Regeneration Medicine, University of California-San Francisco, San Francisco, California 94143, USA. scn@ventricular.org

Country: United States

AGENCY: United States NINDS

GRANT: NS021223

ACRONYM: NS

MEDLINETA: Arch Neurol

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