Construction and characterization of soft-supported lipid bilayer membranes for biosensors application.

Construction and characterization of soft-supported lipid bilayer membranes for biosensors application. Research Abstract Details 

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Construction and characterization of soft-supported lipid bilayer membranes for biosensors application. Abstract Text:

J Jimenez,A J Heim,W G Matthews,N Alcantar,Jeffy Jimenez,August J Heim,W Garrett Matthews,Norma Alcantar,

A model cell membrane can be ingeniously used to mimic biological processes with wide applications in the biomedical field. For instance, a model cell membrane can be used as a functionalized element integrated to a sensor for identification of specific proteins or other molecules in a biofluid. A special characteristic of the model membrane described in this work is the fluidic or surface mobility feature given by a thin film of grafted polymer that serves as a cushion layer to support lipid bilayers. Lipid bilayers were deposited on a polyethylene glycol (PEG) thin film over a polished glass substrate using the Langmuir-Blodgett technique. Topographical characterization of the bilayers was accomplished using atomic force microscopy (AFM). Results revealed that the grafted polymeric PEG cushion layer confers mobility to the model membrane.

Construction and characterization of soft-supported lipid bilayer membranes for biosensors application. Publishing Authors By Initials

J Jimenez,AJ Heim,WG Matthews,N Alcantar,J Jimenez,AJ Heim,WG Matthews,N Alcantar,

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Construction and characterization of soft-supported lipid bilayer membranes for biosensors application. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Conference proceedings : ... Annual International

VOLUME: 1

Page Numbers: 4119-22

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ISSN: 1557-170X

DAY: 23

MONTH: 10

YEAR: 2006

Construction and characterization of soft-supported lipid bilayer membranes for biosensors application. Information

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LANGUAGE: eng

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Grant and Affiliation Information for Construction and characterization of soft-supported lipid bilayer membranes for biosensors application.

AFFILIATION: Dept. of Chem. Eng., Univ. of South Florida, Tampa, FL.

Country: United States

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MEDLINETA: Conf Proc IEEE Eng Med Biol So

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