[Construction and antigenic evaluation of a recombinant MVA virus-like particle expressing HBV C gene.]

[Construction and antigenic evaluation of a recombinant MVA virus-like particle expressing HBV C gene.] Research Abstract Details 

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[Construction and antigenic evaluation of a recombinant MVA virus-like particle expressing HBV C gene.] Abstract Text:

Xiang-Ling Luan,Wei Kong,Su-Jun Liu,Li Lei,Yan Hu,Jun Hou,Hong-Hui Shen,Yi-Chen Wu,Shao-Li You,Pan-Yong Mao,Shao-Jie Xin,Xiang-ling Luan,Wei Kong,Su-jun Liu,Li Lei,Yan Hu,Jun Hou,Hong-hui Shen,Yi-chen Wu,Shao-li You,Pan-yong Mao,Shao-jie Xin,

OBJECTIVE: To construct the virus-like parcel expressing hepatitis B virus (HBV) C gene and identify its immunogencity. METHODS: HBV C gene was cloned into the shuttle vector pSC11, and the resulted plasmid pSC11-C was transfected into modified vaccinia virus Ankara (MVA). RESULTS: pSC11-C was correctly constructed as verified by sequence analysis and PCR, and the recombinant virus-like parcel possessed good immunogencity. CONCLUSION: The MVA-C expressing HBV C gene has been successfully constructed to provide important basis for gene therapy research of chronic HBV infection.

[Construction and antigenic evaluation of a recombinant MVA virus-like particle expressing HBV C gene.] Publishing Authors By Initials

XL Luan,W Kong,SJ Liu,L Lei,Y Hu,J Hou,HH Shen,YC Wu,SL You,PY Mao,SJ Xin,XL Luan,W Kong,SJ Liu,L Lei,Y Hu,J Hou,HH Shen,YC Wu,SL You,PY Mao,SJ Xin,

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[Construction and antigenic evaluation of a recombinant MVA virus-like particle expressing HBV C gene.] Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Nan fang yi ke da xue xue bao = Journal of Souther

VOLUME: 28

Page Numbers: 252-4

Journal Abbreviation: Nan Fang Yi Ke Da Xue Xue Bao

ISSN: 1673-4254

DAY: 5

MONTH: Feb

YEAR: 2008

[Construction and antigenic evaluation of a recombinant MVA virus-like particle expressing HBV C gene.] Information

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LANGUAGE: chi

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AFFILIATION: Postgraduate Medical School of PLA, Beijing 100853, China. E-mail: luanxiangling@sohu.com.

Country: China

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MEDLINETA: Nan Fang Yi Ke Da Xue Xue Bao

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