Concurrent encoding of frequency and amplitude modulation in human auditory cortex: MEG evidence.

Concurrent encoding of frequency and amplitude modulation in human auditory cortex: MEG evidence. Research Abstract Details 

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Concurrent encoding of frequency and amplitude modulation in human auditory cortex: MEG evidence. Abstract Text:

Huan Luo,Yadong Wang,David Poeppel,Jonathan Z Simon,

A natural sound can be described by dynamic changes in envelope (amplitude) and carrier (frequency), corresponding to amplitude modulation (AM) and frequency modulation (FM), respectively. Although the neural responses to both AM and FM sounds are extensively studied in both animals and humans, it is uncertain how they are corepresented when changed simultaneously but independently, as is typical for ecologically natural signals. This study elucidates the neural coding of such sounds in human auditory cortex using magnetoencephalography (MEG). Using stimuli with both sinusoidal modulated envelope (f(AM), 37 Hz) and carrier frequency (f(FM), 0.3-8 Hz), it is demonstrated that AM and FM stimulus dynamics are corepresented in the neural code of human auditory cortex. The stimulus AM dynamics are represented neurally with AM encoding, by the auditory steady-state response (aSSR) at f(AM). For sounds with slowly changing carrier frequency (f(FM) <5 Hz), it is shown that the stimulus FM dynamics are tracked by the phase of the aSSR, demonstrating neural phase modulation (PM) encoding of the stimulus carrier frequency. For sounds with faster carrier frequency change (f(FM) > or = 5 Hz), it is shown that modulation encoding of stimulus FM dynamics persists, but the neural encoding is no longer purely PM. This result is consistent with the recruitment of additional neural AM encoding over and above the original neural PM encoding, indicating that both the amplitude and phase of the aSSR at f(AM) track the stimulus FM dynamics. A neural model is suggested to account for these observations.

Concurrent encoding of frequency and amplitude modulation in human auditory cortex: MEG evidence. Publishing Authors By Initials

H Luo,Y Wang,D Poeppel,JZ Simon,

For similar psychological phenomena and processes: mental processes: perception: auditory perception: pitch perception research abstracts see: psychological phenomena and processes: mental processes: perception: auditory perception: pitch perception research

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Concurrent encoding of frequency and amplitude modulation in human auditory cortex: MEG evidence. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: Journal of neurophysiology

VOLUME: 96

Page Numbers: 2712-23

Journal Abbreviation: J. Neurophysiol.

ISSN: 0022-3077

DAY: 1

MONTH: 03

YEAR: 2006

Concurrent encoding of frequency and amplitude modulation in human auditory cortex: MEG evidence. Information

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LANGUAGE: eng

NlmUniqueID: 375404

Concurrent encoding of frequency and amplitude modulation in human auditory cortex: MEG evidence. Keywords Mesh Terms:

KEYWORDS: Pitch Perception

MESH TERMS: physiology

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Grant and Affiliation Information for Concurrent encoding of frequency and amplitude modulation in human auditory cortex: MEG evidence.

AFFILIATION: Neuroscience and Cognitive Science Program, University of Maryland College Park, 1401 Marie Mount Hall, College Park, MD 20742, USA. huanl@wam.umd.edu

Country: United States

AGENCY: United States NIDCD

GRANT: R01-DC05660

ACRONYM: DC

MEDLINETA: J Neurophysiol

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