Concomitant pulmonary and hepatic toxicity secondary to nitrofurantoin: a case report.

Concomitant pulmonary and hepatic toxicity secondary to nitrofurantoin: a case report. Research Abstract Details 

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Concomitant pulmonary and hepatic toxicity secondary to nitrofurantoin: a case report. Abstract Text:

Adrian F Peall,Aidan Hodges,Adrian F Peall,Aidan Hodges,

ABSTRACT: BACKGROUND: Concomitant pulmonary and hepatic toxicity secondary to nitrofurantoin is a rare but serious complication of the use of Nitrofurantoin. CASE PRESENTATION: A 72 year old woman taking Nitrofurantoin for recurrent urinary sepsis presenting with breathlessness abdominal discomfort and abnormal liver function tests is described. Drug toxicity secondary to Nitrofurantoin was diagnosed. Cessation of the drug and a course of steroids markedly improved her condition. DISCUSSION: We review the drug reactions associated with Nitrofurantoin and suggest an alternative treatment strategy for recurrent urinary sepsis. CONCLUSION: Adverse drug reactions are an important cause of concomitant lung and liver toxicity and the mainstay of treatment is drug withdrawal.

Concomitant pulmonary and hepatic toxicity secondary to nitrofurantoin: a case report. Publishing Authors By Initials

AF Peall,A Hodges,AF Peall,A Hodges,

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Concomitant pulmonary and hepatic toxicity secondary to nitrofurantoin: a case report. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Journal of medical case reports

VOLUME: 1

Page Numbers: 59

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ISSN: 1752-1947

DAY: 1

MONTH: 08

YEAR: 2007

Concomitant pulmonary and hepatic toxicity secondary to nitrofurantoin: a case report. Information

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LANGUAGE: eng

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Grant and Affiliation Information for Concomitant pulmonary and hepatic toxicity secondary to nitrofurantoin: a case report.

AFFILIATION: Respiratory Department, Hawke's Bay Hospital, Hastings, New Zealand. adrianpeall@yahoo.co.uk.

Country: England

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MEDLINETA: J Med Case Reports

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