Concentrations of polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans, and dioxin-like polychlorinated biphenyls in blood collected from 195 pregnant women in Sapporo City, Japan.

Concentrations of polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans, and dioxin-like polychlorinated biphenyls in blood collected from 195 pregnant women in Sapporo City, Japan. Research Abstract Details 

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Concentrations of polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans, and dioxin-like polychlorinated biphenyls in blood collected from 195 pregnant women in Sapporo City, Japan. Abstract Text:

Takashi Todaka,Hironori Hirakawa,Jumboku Kajiwara,Tsuguhide Hori,Kazuhiro Tobiishi,Daisuke Onozuka,Shizue Kato,Seiko Sasaki,Sonomi Nakajima,Yasuaki Saijo,Fumihiro Sata,Reiko Kishi,Takao Iida,Masutaka Furue,Takashi Todaka,Hironori Hirakawa,Jumboku Kajiwara,Tsuguhide Hori,Kazuhiro Tobiishi,Daisuke Onozuka,Shizue Kato,Seiko Sasaki,Sonomi Nakajima,Yasuaki Saijo,Fumihiro Sata,Reiko Kishi,Takao Iida,Masutaka Furue,Takashi Todaka,Hironori Hirakawa,Jumboku Kajiwara,Tsuguhide Hori,Kazuhiro Tobiishi,Daisuke Onozuka,Shizue Kato,Seiko Sasaki,Sonomi Nakajima,Yasuaki Saijo,Fumihiro Sata,Reiko Kishi,Takao Iida,Masutaka Furue,

We measured the concentrations of polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), non-ortho coplanar polychlorinated biphenyls (non-ortho PCBs), and mono-ortho coplanar polychlorinated biphenyls (mono-ortho PCBs) in blood collected between 2002 and 2004 from 195 pregnant women living in Sapporo City of Hokkaido Prefecture, Japan. The present study is one of the few studies in which PCDDs, PCDFs, and dioxin-like PCBs have been measured in the blood of pregnant women. Of the 195 pregnant women, 101 were primipara (mean: 28.8 years) and 94 were multipara (mean: 32.4 years). The arithmetic mean total TEQ concentrations of PCDDs, PCDFs, non-ortho PCBs, and mono-ortho PCBs of primiparous and multiparous mothers in Sapporo City were 17.4 (median: 15.7) and 14.0 (median: 13.9)pgTEQ/glipid, respectively, and the concentrations were in the range of 6.6-43.4 and 3.4-28.2pgTEQ/glipid, respectively. In regard to the relationship between the total TEQ concentrations of PCDDs, PCDFs, non-ortho PCBs, and mono-ortho PCBs in maternal blood and the number of deliveries or age of primiparous and multiparius mothers, the levels of these dioxin-like compounds tended to decrease with increases in the number of deliveries and significantly increased with increasing maternal age in both groups. Furthermore, significant correlations were observed between the total TEQ concentrations of these dioxin-like compounds and the age of primiparae and multiparae. The total TEQ concentration of PCDDs, PCDFs, non-ortho PCBs, and mono-ortho PCBs measured in 195 pregnant women has decreased compared to past levels in Japan for the last several decades. The results of the present study have indicated that dioxin contamination in the blood of young women in Japan is continuing to decrease.

Concentrations of polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans, and dioxin-like polychlorinated biphenyls in blood collected from 195 pregnant women in Sapporo City, Japan. Publishing Authors By Initials

T Todaka,H Hirakawa,J Kajiwara,T Hori,K Tobiishi,D Onozuka,S Kato,S Sasaki,S Nakajima,Y Saijo,F Sata,R Kishi,T Iida,M Furue,T Todaka,H Hirakawa,J Kajiwara,T Hori,K Tobiishi,D Onozuka,S Kato,S Sasaki,S Nakajima,Y Saijo,F Sata,R Kishi,T Iida,M Furue,T Todaka,H Hirakawa,J Kajiwara,T Hori,K Tobiishi,D Onozuka,S Kato,S Sasaki,S Nakajima,Y Saijo,F Sata,R Kishi,T Iida,M Furue,

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Concentrations of polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans, and dioxin-like polychlorinated biphenyls in blood collected from 195 pregnant women in Sapporo City, Japan. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Chemosphere

VOLUME: 69

Page Numbers: 1228-37

Journal Abbreviation: Chemosphere

ISSN: 0045-6535

DAY: 12

MONTH: 07

YEAR: 2007

Concentrations of polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans, and dioxin-like polychlorinated biphenyls in blood collected from 195 pregnant women in Sapporo City, Japan. Information

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LANGUAGE: eng

NlmUniqueID: 320657

Concentrations of polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans, and dioxin-like polychlorinated biphenyls in blood collected from 195 pregnant women in Sapporo City, Japan. Keywords Mesh Terms:

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AFFILIATION: Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, Higashi-ku, Fukuoka 812-8582, Japan.

Country: England

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MEDLINETA: Chemosphere

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