COMT genotype and manic symptoms in schizophrenia.

COMT genotype and manic symptoms in schizophrenia. Research Abstract Details 

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COMT genotype and manic symptoms in schizophrenia. Abstract Text:

Pamela DeRosse,Birgit Funke,Katherine E Burdick,Todd Lencz,Terry E Goldberg,John M Kane,Raju Kucherlapati,Anil K Malhotra,

Inconsistencies in the relation between COMT variation and schizophrenia may be clarified by careful delineation of a target phenotype. The present study reports a significant association between a COMT haplotype and the severity of manic symptoms in 162 patients with schizophrenia or schizoaffective disorder (SZ). These data suggest that the effect of COMT variation may be associated with comorbid manic symptoms in SZ.

COMT genotype and manic symptoms in schizophrenia. Publishing Authors By Initials

P DeRosse,B Funke,KE Burdick,T Lencz,TE Goldberg,JM Kane,R Kucherlapati,AK Malhotra,

For similar investigative techniques: epidemiologic methods: data collection: health surveys: health status indicators: severity of illness index research abstracts see: investigative techniques: epidemiologic methods: data collection: health surveys: health status indicators: severity of illness index research

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MEDLINE DATE:

COMT genotype and manic symptoms in schizophrenia. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: Schizophrenia research

VOLUME: 87

Page Numbers: 28-31

Journal Abbreviation: Schizophr. Res.

ISSN: 0920-9964

DAY: 7

MONTH: 07

YEAR: 2006

COMT genotype and manic symptoms in schizophrenia. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 8804207

COMT genotype and manic symptoms in schizophrenia. Keywords Mesh Terms:

KEYWORDS: Severity of Illness Index

MESH TERMS: genetics

Chemical & Substance for Abstract: COMT genotype and manic symptoms in schizophrenia. Information

Substance Name: Catechol O-Methyltransferase

Registry Number: EC 2.1.1.6

Grant and Affiliation Information for COMT genotype and manic symptoms in schizophrenia.

AFFILIATION: Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore-Long Island Jewish Health System, 75-59 263rd Street, Glen Oaks, NY 11004, and Harvard Partners Center for Genetics and Genomics, Boston, MA, United States. pderosse@lij.edu

Country: Netherlands

AGENCY: United States NIMH

GRANT: MH001760

ACRONYM: MH

MEDLINETA: Schizophr Res

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