Computer-assisted measurement of vessel shape from 3T magnetic resonance angiography of mouse brain.

Computer-assisted measurement of vessel shape from 3T magnetic resonance angiography of mouse brain. Research Abstract Details 

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Computer-assisted measurement of vessel shape from 3T magnetic resonance angiography of mouse brain. Abstract Text:

E Bullitt,S R Aylward,T Van Dyke,W Lin,

Blood vessel morphology (vessel radius, branching pattern, and tortuosity) is altered by a multitude of diseases. Although murine models of human pathology are important to the investigation of many diseases, there are few publications that address quantitative measurements of murine vascular morphology. This report outlines methods of imaging mice in vivo using magnetic resonance angiograms obtained on a clinical 3T unit, of defining mouse vasculature from these images, and of quantifying measures of vessel shape. We provide examples of both healthy and diseased vasculature and illustrate how the approach can be used to assess pathology both visually and quantitatively. The method is amenable to the assessment of many diseases in both human beings and mice.

Computer-assisted measurement of vessel shape from 3T magnetic resonance angiography of mouse brain. Publishing Authors By Initials

E Bullitt,SR Aylward,T Van Dyke,W Lin,

For similar diagnosis: diagnostic techniques and procedures: diagnostic imaging: subtraction technique research abstracts see: diagnosis: diagnostic techniques and procedures: diagnostic imaging: subtraction technique research

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Computer-assisted measurement of vessel shape from 3T magnetic resonance angiography of mouse brain. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: Methods (San Diego, Calif.)

VOLUME: 43

Page Numbers: 29-34

Journal Abbreviation: Methods

ISSN: 1046-2023

DAY: 3

MONTH: Sep

YEAR: 2007

Computer-assisted measurement of vessel shape from 3T magnetic resonance angiography of mouse brain. Information

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LANGUAGE: eng

NlmUniqueID: 9426302

Computer-assisted measurement of vessel shape from 3T magnetic resonance angiography of mouse brain. Keywords Mesh Terms:

KEYWORDS: Subtraction Technique

MESH TERMS: methods

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Grant and Affiliation Information for Computer-assisted measurement of vessel shape from 3T magnetic resonance angiography of mouse brain.

AFFILIATION: Department of Surgery and CASILab, University of North Carolina, Chapel Hill, 219 Wing E, CB# 7062, NC 27599, USA. bullitt@med.unc.edu

Country: United States

AGENCY: United States NIBIB

GRANT: R01 EB000219

ACRONYM: EB

MEDLINETA: Methods

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