Complete Sequence and Analysis of the Mitochondrial Genome of Hemiselmis andersenii CCMP644 (Cryptophyceae).

Complete Sequence and Analysis of the Mitochondrial Genome of Hemiselmis andersenii CCMP644 (Cryptophyceae). Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Complete Sequence and Analysis of the Mitochondrial Genome of Hemiselmis andersenii CCMP644 (Cryptophyceae). Abstract Text:

BACKGROUND: Cryptophytes are an enigmatic group of unicellular eukaryotes with plastids derived by secondary (i.e., eukaryote-eukaryote) endosymbiosis. Cryptophytes are unusual in that they possess four genomes-a host cell-derived nuclear and mitochondrial genome and an endosymbiont-derived plastid and 'nucleomorph' genome. The evolutionary origins of the host and endosymbiont components of cryptophyte algae are at present poorly understood. Thus far, a single complete mitochondrial genome sequence has been determined for the cryptophyte Rhodomonas salina. Here, the second complete mitochondrial genome of the cryptophyte alga Hemiselmis andersenii CCMP644 is presented. RESULTS: The H. andersenii mtDNA is 60,553 bp in size and encodes 30 structural RNAs and 36 protein-coding genes, all located on the same strand. A prominent feature of the genome is the presence of a approximately 20 Kbp long intergenic region comprised of numerous tandem and dispersed repeat units of between 22-336 bp. Adjacent to these repeats are 27 copies of palindromic sequences predicted to form stable DNA stem-loop structures. One such stem-loop is located near a GC-rich and GC-poor region and may have a regulatory function in replication or transcription. The H. andersenii mtDNA shares a number of features in common with the genome of the cryptophyte Rhodomonas salina, including general architecture, gene content, and the presence of a large repeat region. However, the H. andersenii mtDNA is devoid of inverted repeats and introns, which are present in R. salina. Comparative analyses of the suite of tRNAs encoded in the two genomes reveal that the H. andersenii mtDNA has lost or converted its original trnK(uuu) gene and possesses a trnS-derived 'trnK(uuu)', which appears unable to produce a functional tRNA. Mitochondrial protein coding gene phylogenies strongly support a variety of previously established eukaryotic groups, but fail to resolve the relationships among higher-order eukaryotic lineages. CONCLUSION: Comparison of the H. andersenii and R. salina mitochondrial genomes reveals a number of cryptophyte-specific genomic features, most notably the presence of a large repeat-rich intergenic region. However, unlike R. salina, the H. andersenii mtDNA does not possess introns and lacks a Lys-tRNA, which is presumably imported from the cytosol.

Complete Sequence and Analysis of the Mitochondrial Genome of Hemiselmis andersenii CCMP644 (Cryptophyceae). Publishing Authors By Initials

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Complete Sequence and Analysis of the Mitochondrial Genome of Hemiselmis andersenii CCMP644 (Cryptophyceae). Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: BMC genomics

VOLUME: 9

Page Numbers: 215

Journal Abbreviation: BMC Genomics

ISSN: 1471-2164

DAY: 12

MONTH: 05

YEAR: 2008

Complete Sequence and Analysis of the Mitochondrial Genome of Hemiselmis andersenii CCMP644 (Cryptophyceae). Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 100965258

Complete Sequence and Analysis of the Mitochondrial Genome of Hemiselmis andersenii CCMP644 (Cryptophyceae). Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Complete Sequence and Analysis of the Mitochondrial Genome of Hemiselmis andersenii CCMP644 (Cryptophyceae). Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Complete Sequence and Analysis of the Mitochondrial Genome of Hemiselmis andersenii CCMP644 (Cryptophyceae).

AFFILIATION: Canadian Institute for Advanced Research, Integrated Microbial Biodiversity Program, Department of Biochemistry and Molecular Biology, Dalhousie University, Halifax, Nova Scotia, Canada. eunsookim@dal.ca

Country: England

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: BMC Genomics

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Complete Sequence and Analysis of the Mitochondrial Genome of Hemiselmis andersenii CCMP644 Cryptophyceae Related Publications

• A retrospective study of return to work following surgery.
• Alcoholism--a public health problem.
• Challenges for management of the diabetic foot in Africa: doing more with less.
• Clinical research in head and neck reconstruction.
• Complete Sequence and Analysis of the Mitochondrial Genome of Hemiselmis andersenii CCMP644 (Cryptophyceae).
• Epidermolysis bullosa dystorphica and systemic lupus erythematosus.
• Evolutionary dynamics of light-independent protochlorophyllide oxidoreductase genes in the secondary plastids of cryptophyte algae.
• Field trials of new antimalarials in West Africa.
• HIV Testing among Canadian Tuberculosis Cases from 1997 to 1998.
• HIV/AIDS--the new "great teacher".
• Influence of maternal malaria on newborn infants.
• International convention on psychotropic drugs.
• Lateral transfer of introns in the cryptophyte plastid genome.
• Leg bracing in hemiplegia.
• Lepromatous leprosy presenting with swelling of the legs.
• Modelling the evolution of drug resistance in the presence of antiviral drugs.
• Novel nucleomorph genome architecture in the cryptomonad genus hemiselmis.
• Nucleomorph genome of Hemiselmis andersenii reveals complete intron loss and compaction as a driver of protein structure and function.
• Organelle Evolution: What's in a Name?
• Perforation of the nasal septum due to soda ash.
• Probing key coordination interactions: configurationally restricted metal activated CXCR4 antagonists.
• ROBERT GEORGE ARCHIBALD.
• Small molecule CXCR4 chemokine receptor antagonists: developing drug candidates.
• Some comments on nutrition education.
• Structural analysis and haplotype diversity in swine LEP and MC4R genes.
• THE CARBON DIOXIDE RESPONSE CURVE OF THE DOG AT SEA LEVEL AND AT ALTITUDE. AMRL-TR-64-145.
• The Technologizing of EH&S.
• The eukaryotic tree of life: endosymbiosis takes its TOL.
• Why I became an occupational physician ...
• Working memory and learning in children with developmental coordination disorder and specific language impairment.