The origin of image artifacts in an off-resonance spin-locking experiment is shown to be imperfections in the excitation flip angle. A pulse sequence for off-resonance spin locking is implemented that compensates for imperfections in the excitation flip angle through an off-resonance rotary echo. The off-resonance rotary echo alternates the frequency offset and phase of the RF transmitter during two spin-locking pulses of equal duration. The underlying theory is detailed, and MR images demonstrate the effectiveness of the technique in agarose gel phantoms and in in vivo human brain at 3T.
Compensation for spin-lock artifacts using an off-resonance rotary echo in T1rhooff-weighted imaging. Publishing Authors By Initials
Compensation for spin-lock artifacts using an off-resonance rotary echo in T1rhooff-weighted imaging. Journal Published:
PUBLICATION TYPE: Research Support, N.I.H., Extr
Journal: Magnetic resonance in medicine : official journal
VOLUME: 57
Page Numbers: 2-7
Journal Abbreviation:
ISSN: 0740-3194
DAY: 3
MONTH: Jan
YEAR: 2007
Compensation for spin-lock artifacts using an off-resonance rotary echo in T1rhooff-weighted imaging. Information
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LANGUAGE: eng
NlmUniqueID: 8505245
Compensation for spin-lock artifacts using an off-resonance rotary echo in T1rhooff-weighted imaging. Keywords Mesh Terms:
KEYWORDS: Reference Values
MESH TERMS: methods
Chemical & Substance for Abstract: Compensation for spin-lock artifacts using an off-resonance rotary echo in T1rhooff-weighted imaging. Information
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Grant and Affiliation Information for Compensation for spin-lock artifacts using an off-resonance rotary echo in T1rhooff-weighted imaging.
AFFILIATION: Department of Biochemistry & Molecular Biophysics, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6100, USA. witschey@med.upenn.edu
Country: United States
AGENCY: United States NIAMS
GRANT: R01AR051041
ACRONYM: AR
MEDLINETA: Magn Reson Med
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