Comparison of unenhanced CT and chemical shift MRI in evaluating lipid-rich adrenal adenomas.

Comparison of unenhanced CT and chemical shift MRI in evaluating lipid-rich adrenal adenomas. Research Abstract Details 

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Comparison of unenhanced CT and chemical shift MRI in evaluating lipid-rich adrenal adenomas. Abstract Text:

Gary M Israel,Melvyn Korobkin,Chun Wang,Elizabeth N Hecht,Glenn A Krinsky,

OBJECTIVE: Our aim was to evaluate adrenal adenomas in patients who underwent both unenhanced CT and chemical shift MRI to determine if adenomas can be characterized with MRI when the findings of CT are indeterminate. MATERIALS AND METHODS: Between January 1999 and June 2003, 40 patients (42 adrenal masses) underwent unenhanced CT and chemical shift MRI and were retrospectively analyzed. Hounsfield units, adrenal-to-spleen chemical shift ratio, and signal-intensity index were obtained for each adrenal mass. Qualitative analysis for loss of signal in each adrenal mass on the opposed-phase images was also performed by two reviewers and compared with the quantitative analyses. A lipid-rich adenoma was diagnosed if the mass measured equal to or less than 10 H, had an adrenal-to-spleen chemical shift ratio of less than 0.71, and had a signal-intensity index of greater than 16.5% or if the mass fulfilled two of the preceding criteria and had follow-up imaging without change. RESULTS: The sensitivities and specificities for diagnosing a lipid-rich adenoma using the qualitative, adrenal-to-spleen chemical shift ratio, signal-intensity index, and unenhanced CT attenuation analyses were 92% (33/36) and 17% (1/6), 100% (36/36) and 100% (6/6), 100% (36/36) and 67% (4/6), and 78% (28/36) and 83% (5/6), respectively. Twenty-eight (67%) lipid-rich adenomas measured equal to or less than 10 H, had an adrenal-to-spleen chemical shift ratio of less than 0.71, and had a signal-intensity index of greater than 16.5%. Eight masses (19%) measured greater than 10 H but had an adrenal-to-spleen chemical shift ratio of less than 0.71 and a signal-intensity index greater than 16.5% and were unchanged at follow-up. CONCLUSION: Eight (62%) of 13 adrenal adenomas measuring greater than 10 H on unenhanced CT were definitively characterized with chemical shift MRI.

Comparison of unenhanced CT and chemical shift MRI in evaluating lipid-rich adrenal adenomas. Publishing Authors By Initials

GM Israel,M Korobkin,C Wang,EN Hecht,GA Krinsky,

For similar tomography, x-ray computed research abstracts see: tomography, x-ray computed research

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Comparison of unenhanced CT and chemical shift MRI in evaluating lipid-rich adrenal adenomas. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: AJR. American journal of roentgenology

VOLUME: 183

Page Numbers: 215-9

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ISSN: 0361-803X

DAY: 15

MONTH: Jul

YEAR: 2004

Comparison of unenhanced CT and chemical shift MRI in evaluating lipid-rich adrenal adenomas. Information

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LANGUAGE: eng

NlmUniqueID: 7708173

Comparison of unenhanced CT and chemical shift MRI in evaluating lipid-rich adrenal adenomas. Keywords Mesh Terms:

KEYWORDS: Tomography, X-Ray Computed

MESH TERMS: diagnosis

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Grant and Affiliation Information for Comparison of unenhanced CT and chemical shift MRI in evaluating lipid-rich adrenal adenomas.

AFFILIATION: Department of Radiology, NYU Medical Center, 560 First Ave., Ste. HW 202, New York, NY 10016, USA. gary.israel@med.nyu.edu

Country: United States

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MEDLINETA: AJR Am J Roentgenol

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