[Comparison of unconsciousness prediction probability with approximate entropy and bispectral index during sedation]

[Comparison of unconsciousness prediction probability with approximate entropy and bispectral index during sedation] Research Abstract Details 

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[Comparison of unconsciousness prediction probability with approximate entropy and bispectral index during sedation] Abstract Text:

Ming-wen Ouyang,Hong Zhang,

OBJECTIVE: To compare the unconsciousness prediction probability (Pk) estimated by approximate entropy (ApEn) and bispectral index (BIS) during the sedation produced by target-controlled infusion (TCI) of propofol. METHODS: Twenty patients (ASA class I-II) scheduled for elective lower limb operations under epidural anesthesia were studied. TCI of propofol was initiated at target plasma concentration of 0.5 microg/ml, and increased by 0.3 to 0.5 microg/ml until loss of consciousness, and then decreased until consciousness recovery. Each target plasma concentration of propofol lasted for 12 min. ApEn and BIS were recorded simultaneously during the periods of consciousness and unconsciousness every 3 min. The Pk of unconsciousness with ApEn and BIS were calculated and compared. RESULTS: ApEn was 0.84+/-0.05 in the state of consciousness and 0.71+/-0.06 upon loss of consciousness, and BIS in the corresponding stages were 80.2+/-6.2 and 67.3+/-7.9, respectively. The Pk of unconsciousness between ApEn (Pk=0.97+/-0.06) and BIS (Pk=0.91+/-0.11) did not significantly differ (P>0.05). CONCLUSION: ApEn as well as BIS is acceptable for predicting consciousness and unconsciousness produced by TCI propofol.

[Comparison of unconsciousness prediction probability with approximate entropy and bispectral index during sedation] Publishing Authors By Initials

MW Ouyang,H Zhang,

For similar organic chemicals: phenols: propofol research abstracts see: organic chemicals: phenols: propofol research

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[Comparison of unconsciousness prediction probability with approximate entropy and bispectral index during sedation] Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Nan fang yi ke da xue xue bao = Journal of Souther

VOLUME: 26

Page Numbers: 287-9

Journal Abbreviation: Nan Fang Yi Ke Da Xue Xue Bao

ISSN: 1673-4254

DAY: 14

MONTH: Mar

YEAR: 2006

[Comparison of unconsciousness prediction probability with approximate entropy and bispectral index during sedation] Information

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LANGUAGE: chi

NlmUniqueID: 101266132

[Comparison of unconsciousness prediction probability with approximate entropy and bispectral index during sedation] Keywords Mesh Terms:

KEYWORDS: Propofol

MESH TERMS: pharmacology

Chemical & Substance for Abstract: [Comparison of unconsciousness prediction probability with approximate entropy and bispectral index during sedation] Information

Substance Name: Propofol

Registry Number: 2078-54-8

Grant and Affiliation Information for [Comparison of unconsciousness prediction probability with approximate entropy and bispectral index during sedation]

AFFILIATION: Department of Anesthesiology, General Hospital of PLA, Beijing 100853, China. ouyangmm2008@yahoo.com.cn

Country: China

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MEDLINETA: Nan Fang Yi Ke Da Xue Xue Bao

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