Comparison of the healing process in plated and non-plated fractures of the mandible in rats.

Comparison of the healing process in plated and non-plated fractures of the mandible in rats. Research Abstract Details 

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Comparison of the healing process in plated and non-plated fractures of the mandible in rats. Abstract Text:

L Rasubala,H Yoshikawa,A A S Islam,K Nagata,T Iijima,M Ohishi,

We compared the healing process of plated and non-plated fractures. The mandibles of 72 male Wistar rats were fractured and more either plated or not plated (n = 36 in each group). The healing process of the two conditions was studied histologically and immunohistochemically using a specific antibody to bone morphogenetic protein-2 (BMP-2). The results showed that the healing process in the plated group was delayed by one week compared with the non-plated group. Trauma to the surrounding soft tissues affected the healing process. BMP-2 was expressed at all stages in both groups. We conclude that the healing process is disturbed by the fixing of a plate; that periosteum is one of the main sources of osteogenic cells; and that BMP-2 is an important regulator of morphogenesis.

Comparison of the healing process in plated and non-plated fractures of the mandible in rats. Publishing Authors By Initials

L Rasubala,H Yoshikawa,AA Islam,K Nagata,T Iijima,M Ohishi,

For similar peptides: intercellular signaling peptides and proteins: cytokines: transforming growth factor beta research abstracts see: peptides: intercellular signaling peptides and proteins: cytokines: transforming growth factor beta research

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Comparison of the healing process in plated and non-plated fractures of the mandible in rats. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: The British journal of oral & maxillofacial surger

VOLUME: 42

Page Numbers: 315-22

Journal Abbreviation:

ISSN: 0266-4356

DAY: 19

MONTH: Aug

YEAR: 2004

Comparison of the healing process in plated and non-plated fractures of the mandible in rats. Information

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LANGUAGE: eng

NlmUniqueID: 8405235

Comparison of the healing process in plated and non-plated fractures of the mandible in rats. Keywords Mesh Terms:

KEYWORDS: Transforming Growth Factor beta

MESH TERMS: physiology

Chemical & Substance for Abstract: Comparison of the healing process in plated and non-plated fractures of the mandible in rats. Information

Substance Name: bone morphogenetic protein 2

Registry Number: 0

Grant and Affiliation Information for Comparison of the healing process in plated and non-plated fractures of the mandible in rats.

AFFILIATION: Department of Oral and Maxillofacial Oncology, Division of Maxillofacial Diagnostic and Surgical Sciences, Faculty of Dental Science, Kyushu University, Fukuoka 812-8582, Japan. rasubala@bioreg.kyushu-u.ac.jp

Country: Scotland

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MEDLINETA: Br J Oral Maxillofac Surg

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