Comparison of standard- and low-radiation-dose CT for quantification of emphysema.

Comparison of standard- and low-radiation-dose CT for quantification of emphysema. Research Abstract Details 

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Comparison of standard- and low-radiation-dose CT for quantification of emphysema. Abstract Text:

David S Gierada,Thomas K Pilgram,Bruce R Whiting,Cheng Hong,Andrew J Bierhals,Jin Hwan Kim,Kyongtae T Bae,David S Gierada,Thomas K Pilgram,Bruce R Whiting,Cheng Hong,Andrew J Bierhals,Jin Hwan Kim,Kyongtae T Bae,

OBJECTIVE: This study was performed to compare standard- and low-radiation-dose techniques in the CT quantification of emphysema. MATERIALS AND METHODS: The study population consisted of 36 men and 20 women who were current or former heavy smokers and underwent standard-dose (effective tube current, 100-250 mAs) chest CT at our institution within 6 months of having undergone low-dose (effective tube current, 30-60 mAs) chest CT. All CT scans were reconstructed at 5-mm slice thickness with a smooth filter. CT-measured lung volume, mean and median lung attenuation, and percentage of lung volume with attenuation lower than multiple thresholds (emphysema index values) were compared by Pearson correlation, two-tailed and paired Student's t tests, and regression analysis. RESULTS: There were no significant differences in mean attenuation (-848 vs -846 H, p > 0.35) for the low dose and the standard dose or in median lung attenuation (-879 vs -878 H, p > 0.66). Low- and standard-dose emphysema indexes were correlated at all attenuation thresholds (r = 0.86-0.97). Mean emphysema indexes were higher on the low-dose scans, but the mean difference at all thresholds was less than 3%. The differences were significant (p < 0.05) only at the lower index thresholds, correlated with differences in lung volume (r < or = 0.86), and increased with greater differences in dose. CONCLUSION: Low-dose technique has minimal effect on CT quantification of emphysema.

Comparison of standard- and low-radiation-dose CT for quantification of emphysema. Publishing Authors By Initials

DS Gierada,TK Pilgram,BR Whiting,C Hong,AJ Bierhals,JH Kim,KT Bae,DS Gierada,TK Pilgram,BR Whiting,C Hong,AJ Bierhals,JH Kim,KT Bae,

For similar tomography, x-ray computed research abstracts see: tomography, x-ray computed research

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Comparison of standard- and low-radiation-dose CT for quantification of emphysema. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: AJR. American journal of roentgenology

VOLUME: 188

Page Numbers: 42-7

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ISSN: 1546-3141

DAY: 3

MONTH: Jan

YEAR: 2007

Comparison of standard- and low-radiation-dose CT for quantification of emphysema. Information

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LANGUAGE: eng

NlmUniqueID: 7708173

Comparison of standard- and low-radiation-dose CT for quantification of emphysema. Keywords Mesh Terms:

KEYWORDS: Tomography, X-Ray Computed

MESH TERMS: methods

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Grant and Affiliation Information for Comparison of standard- and low-radiation-dose CT for quantification of emphysema.

AFFILIATION: Mallinckrodt Institute of Radiology, Washington University School of Medicine, 510 S Kingshighway Blvd., St. Louis, MO 63110, USA. gieradad@wustl.edu

Country: United States

AGENCY: United States NHLBI

GRANT: R01HL72369

ACRONYM: HL

MEDLINETA: AJR Am J Roentgenol

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